Human EpCAM/TROP-1 Antibody | R&D Systems MAB960 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human EpCAM/TROP-1 Antibody

catalog :

MAB960

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

158210

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 7

Reference
Witek M, Aufforth R, Wang H, Kamande J, Jackson J, Pullagurla S, et al. Discrete microfluidics for the isolation of circulating tumor cell subpopulations targeting fibroblast activation protein alpha and epithelial cell adhesion molecule. NPJ Precis Oncol. 2017;1: pubmed publisher
Mitchell M, Webster J, Chung A, Guimarães P, Khan O, Langer R. Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis. Nat Commun. 2017;8:14179 pubmed publisher
Hsu Y, Osmulski P, Wang Y, Huang Y, Liu L, Ruan J, et al. EpCAM-Regulated Transcription Exerts Influences on Nanomechanical Properties of Endometrial Cancer Cells That Promote Epithelial-to-Mesenchymal Transition. Cancer Res. 2016;76:6171-6182 pubmed
Krampitz G, George B, Willingham S, Volkmer J, Weiskopf K, Jahchan N, et al. Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors. Proc Natl Acad Sci U S A. 2016;113:4464-9 pubmed publisher
Zhao X, Parpart S, Takai A, Roessler S, Budhu A, Yu Z, et al. Integrative genomics identifies YY1AP1 as an oncogenic driver in EpCAM(+) AFP(+) hepatocellular carcinoma. Oncogene. 2015;34:5095-104 pubmed publisher
MacArthur K, Kao G, Chandrasekaran S, Alonso Basanta M, Chapman C, Lustig R, et al. Detection of brain tumor cells in the peripheral blood by a telomerase promoter-based assay. Cancer Res. 2014;74:2152-9 pubmed publisher
Yamashita T, Budhu A, Forgues M, Wang X. Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma. Cancer Res. 2007;67:10831-9 pubmed

product information

brand :

R&D Systems

master code :

MAB960

SKU :

MAB960-100

product name :

Human EpCAM/TROP-1 Antibody

description :

The Human EpCAM/TROP-1 Antibody from R&D Systems is a mouse monoclonal antibody to EpCAM/TROP1. This antibody reacts with human. The Human EpCAM/TROP-1 Antibody has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry.

target :

EpCAM/TROP1

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

158210

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human EpCAM, Gln24-Lys265, Accession # P16422

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human EpCAM in direct ELISAs and Western blots. This antibody detects an epitope found in the extracellular domain between amino acids 136 and 265. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) ALCAM, rhBCAM, rhMCAM, rhNCAM-L1, or rmOCAM is observed.

gene symbol :

EPCAM

catalog number base :

MAB960

accessionNumbers :

P16422

applications :

Western Blot, Immunohistochemistry, Immunocytochemistry

2020 USD :

339

2021 USD :

359 USD

alt names :

17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2, GA733-2EGP34, gp40, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.