Human EpCAM/TROP-1 Antibody | R&D Systems MAB960-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human EpCAM/TROP-1 Antibody

catalog :

MAB960-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

158210

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 14

Reference
Kim K, Kang Y, Park S, Kim D, Lee S, Ko K, et al. Effect of leaf position and days post-infiltration on transient expression of colorectal cancer vaccine candidate proteins GA733-Fc and GA733-FcK in Nicotiana benthamiana plant. Peerj. 2021;9:e10851 pubmed publisher
Lee Y, Lim C, Lim S, Park S, Hong J, Kim J, et al. Expression of Colorectal Cancer Antigenic Protein Fused to IgM Fc in Chinese Cabbage (Brassica rapa). Plants (Basel). 2020;9: pubmed publisher
Kumar T, Soares R, Ali Dholey L, Ramachandraiah H, Aval N, Aljadi Z, et al. Multi-layer assembly of cellulose nanofibrils in a microfluidic device for the selective capture and release of viable tumor cells from whole blood. Nanoscale. 2020;12:21788-21797 pubmed publisher
Wei P, Wu F, Kang B, Sun X, Heskia F, Pachot A, et al. Plasma extracellular vesicles detected by Single Molecule array technology as a liquid biopsy for colorectal cancer. J Extracell Vesicles. 2020;9:1809765 pubmed publisher
Witek M, Aufforth R, Wang H, Kamande J, Jackson J, Pullagurla S, et al. Discrete microfluidics for the isolation of circulating tumor cell subpopulations targeting fibroblast activation protein alpha and epithelial cell adhesion molecule. NPJ Precis Oncol. 2017;1: pubmed publisher
Mitchell M, Webster J, Chung A, Guimarães P, Khan O, Langer R. Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis. Nat Commun. 2017;8:14179 pubmed publisher
Hsu Y, Osmulski P, Wang Y, Huang Y, Liu L, Ruan J, et al. EpCAM-Regulated Transcription Exerts Influences on Nanomechanical Properties of Endometrial Cancer Cells That Promote Epithelial-to-Mesenchymal Transition. Cancer Res. 2016;76:6171-6182 pubmed
Cai Z, Zhang A, Choksi S, Li W, Li T, Zhang X, et al. Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration. Cell Res. 2016;26:886-900 pubmed publisher
Krampitz G, George B, Willingham S, Volkmer J, Weiskopf K, Jahchan N, et al. Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors. Proc Natl Acad Sci U S A. 2016;113:4464-9 pubmed publisher
Chung V, Tan T, Tan M, Wong M, Kuay K, Yang Z, et al. GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification. Sci Rep. 2016;6:19943 pubmed publisher
Zhou F, Qi Y, Xu H, Wang Q, Gao X, Guo H. Expression of EpCAM and Wnt/ Î²-catenin in human colon cancer. Genet Mol Res. 2015;14:4485-94 pubmed publisher
Zhao X, Parpart S, Takai A, Roessler S, Budhu A, Yu Z, et al. Integrative genomics identifies YY1AP1 as an oncogenic driver in EpCAM(+) AFP(+) hepatocellular carcinoma. Oncogene. 2015;34:5095-104 pubmed publisher
MacArthur K, Kao G, Chandrasekaran S, Alonso Basanta M, Chapman C, Lustig R, et al. Detection of brain tumor cells in the peripheral blood by a telomerase promoter-based assay. Cancer Res. 2014;74:2152-9 pubmed publisher
Yamashita T, Budhu A, Forgues M, Wang X. Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma. Cancer Res. 2007;67:10831-9 pubmed

product information

brand :

R&D Systems

master code :

MAB960

SKU :

MAB960-100

product name :

Human EpCAM/TROP-1 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human EpCAM/TROP-1 Antibody from R&D Systems is a mouse monoclonal antibody to EpCAM/TROP1. This antibody reacts with human,mouse,plant - nicotiana benthamiana,xenograft. The Human EpCAM/TROP-1 Antibody has been validated for the following applications: Multiplex Immunofluorescence,Adhesion Assay,Cell Capture,Phagocytosis Assay,Flow Cytometry,Western Blot,Neutralization,ELISA Capture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry.

target :

EpCAM/TROP1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

158210

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Immunohistochemistry 8-25 ug/mL, Immunocytochemistry 8-25 ug/mL, Multiplex Immunofluorescence 3-25 ug/mL

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human EpCAM/TROP-1, Gln24-Lys265, Accession # P16422

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Plant - Nicotiana benthamiana,Xenograft

specificity :

Detects human EpCAM/TROP-1 in direct ELISAs and Western blots. This antibody detects an epitope found in the extracellular domain between amino acids 136 and 265. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) ALCAM, rhBCAM, rhMCAM, rhNCAM-L1, or recombinant mouse (rm) OCAM is observed. In direct ELISAs, less than 5% cross-reactivity with rmEpCAM/TROP-1 is observed.

gene symbol :

EPCAM

accessionNumbers :

P16422

applications :

Multiplex Immunofluorescence,Adhesion Assay,Cell Capture,Phagocytosis Assay,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Neutralization,Immunocytochemistry,ELISA Capture

USD :

489 USD

alt names :

17-1A, 323/A3, ACSTD1, antigen identified by monoclonal AUA1, CD326, CD326 antigen, Cell surface glycoprotein Trop-1, chromosome 4, surface marker (35kD glycoprotein), DIAR5, EGP, EGP-2, EGP314, EGP40, EpCAM, epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, ESA, GA733-2, GA733-2EGP34, gp40, hEGP314, HNPCC8, KS 1/4 antigen, KS1/4, KSAHEA125, M1S2, M4S1, M4S1Ly74, Major gastrointestinal tumor-associated protein GA733-2, MIC18MH99, MOC31, TACST-1, TACSTD1, TROP1, TROP1CD326, Tumor-associated calcium signal transducer 1CO-17A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage