product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ErbB2/Her2 (Research Grade Trastuzumab Biosimilar) Antibody
catalog :
MAB9589-100
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
monoclonal
host :
human
conjugate :
nonconjugated
clone name :
Hu5
reactivity :
human
application :
western blot, immunoprecipitation, flow cytometry
more info or order :
R&D Systems product webpage
citations: 4
Reference
Mortales C, Dutzar B, Chen J, Chen A, Huard J, Walkey C, et al. NL-201 Upregulates MHC-I Expression and Intratumoral T-cell Receptor Diversity, and Demonstrates Robust Antitumor Activity as Monotherapy and in Combination with PD-1 Blockade. Cancer Immunol Res. 2023;11:1000-1010 pubmed publisher
Shaimerdenova M, Ayupova T, Bekmurzayeva A, Sypabekova M, Ashikbayeva Z, Tosi D. Spatial-Division Multiplexing Approach for Simultaneous Detection of Fiber-Optic Ball Resonator Sensors: Applications for Refractometers and Biosensors. Biosensors (Basel). 2022;12: pubmed publisher
Vogl T, Klompus S, Leviatan S, Kalka I, Weinberger A, Wijmenga C, et al. Population-wide diversity and stability of serum antibody epitope repertoires against human microbiota. Nat Med. 2021;27:1442-1450 pubmed publisher
Chen Y, Wang R, Huang S, Henson E, Bi J, Gibson S. Erb-b2 Receptor Tyrosine Kinase 2 (ERBB2) Promotes ATG12-Dependent Autophagy Contributing to Treatment Resistance of Breast Cancer Cells. Cancers (Basel). 2021;13: pubmed publisher
product information
master code :
MAB9589
SKU :
MAB9589-100
product name :
Human ErbB2/Her2 (Research Grade Trastuzumab Biosimilar) Antibody
unit size :
100 ug (also 25 ug)
description :
The Human ErbB2/Her2 (Research Grade Trastuzumab Biosimilar) Antibody from R&D Systems is a human monoclonal antibody to ErbB2/Her2. This antibody reacts with human,bacteria - staphylococcus,bacteria - streptococcus. The Human ErbB2/Her2 (Research Grade Trastuzumab Biosimilar) Antibody has been validated for the following applications: Neutralization Control,Flow Cytometry,Immunoprecipitation,Western Blot,Inhibition of Cell Growth,CyTOF-ready.
target :
ErbB2/Her2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
Hu5
conjugate :
Unconjugated
host :
Human
immunogen :
Human ErbB2/Her2
isotype :
IgG1
purity :
Protein A or G purified from cell culture supernatant
species :
Human,Bacteria - Staphylococcus,Bacteria - Streptococcus
specificity :
Detects human ErbB2/Her2 in direct ELISAs. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Trastuzumab. This product is for research use only.
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of ErbB2/Her2 antibody in MCF-7 human cell line antibody by Flow Cytometry.
applications :
Neutralization Control,Flow Cytometry,Immunoprecipitation,Western Blot,Inhibition of Cell Growth,CyTOF-ready
extended description :
Recombinant Monoclonal Antibody For Research Use Only
USD :
469 USD
product details :
Recombinant Monoclonal Antibody For Research Use Only
alt names :
CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER2, HER-2, HER2EC 2.7.10.1, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, Neu Oncogene, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGL, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, TKR1, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.