Human/Primate GDF-15 Antibody | R&D Systems MAB957-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Primate GDF-15 Antibody

catalog :

MAB957-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

147627

reactivity :

human, mouse

application :

western blot, ELISA, neutralization

more info or order :

R&D Systems product webpage

citations: 16

Reference
Wang S, Chang Y, Fang W, Li A, Chen C, Yeh T, et al. Growth differentiation factor 15 induces cisplatin resistance through upregulation of xCT expression and glutathione synthesis in gastric cancer. Cancer Sci. 2023;: pubmed publisher
Radwanska A, Cottage C, Piras A, Overed Sayer C, Sihlbom C, Budida R, et al. Increased expression and accumulation of GDF15 in IPF extracellular matrix contribute to fibrosis. JCI Insight. 2022;7: pubmed publisher
Chang J, Chang E, Lee Y, Cha Y, Cha S, Cho W, et al. Hyperbaric Oxygen Exposure Attenuates Circulating Stress Biomarkers: A Pilot Interventional Study. Int J Environ Res Public Health. 2020;17: pubmed publisher
Huang J, Wang Y, Lo S, Tseng L, Chen D, Wu Y, et al. Visfatin Mediates Malignant Behaviors through Adipose-Derived Stem Cells Intermediary in Breast Cancer. Cancers (Basel). 2019;12: pubmed publisher
Melvin A, Lacerda E, Dockrell H, O Rahilly S, Nacul L. Circulating levels of GDF15 in patients with myalgic encephalomyelitis/chronic fatigue syndrome. J Transl Med. 2019;17:409 pubmed publisher
Chen G, Wang M, Liu X. GDF15 promotes osteosarcoma cell migration and invasion by regulating the TGF‑β signaling pathway. Mol Med Rep. 2019;20:4262-4270 pubmed publisher
Olsen O, Skjærvik A, Størdal B, Sundan A, Holien T. TGF-? contamination of purified recombinant GDF15. PLoS ONE. 2017;12:e0187349 pubmed publisher
Li C, Wang X, Casal I, Wang J, Li P, Zhang W, et al. Growth differentiation factor 15 is a promising diagnostic and prognostic biomarker in colorectal cancer. J Cell Mol Med. 2016;20:1420-6 pubmed publisher
Maetzler W, Deleersnijder W, Hanssens V, Bernard A, Brockmann K, Marquetand J, et al. GDF15/MIC1 and MMP9 Cerebrospinal Fluid Levels in Parkinson's Disease and Lewy Body Dementia. PLoS ONE. 2016;11:e0149349 pubmed publisher
Li C, Wang J, Kong J, Tang J, Wu Y, Xu E, et al. GDF15 promotes EMT and metastasis in colorectal cancer. Oncotarget. 2016;7:860-72 pubmed publisher
Uchiyama T, Kawabata H, Miura Y, Yoshioka S, Iwasa M, Yao H, et al. The role of growth differentiation factor 15 in the pathogenesis of primary myelofibrosis. Cancer Med. 2015;4:1558-72 pubmed publisher
Li J, Veltri R, Yuan Z, Christudass C, Mandecki W. Macrophage inhibitory cytokine 1 biomarker serum immunoassay in combination with PSA is a more specific diagnostic tool for detection of prostate cancer. PLoS ONE. 2015;10:e0122249 pubmed publisher
Tanno T, Lim Y, Wang Q, Chesi M, Bergsagel P, Matthews G, et al. Growth differentiating factor 15 enhances the tumor-initiating and self-renewal potential of multiple myeloma cells. Blood. 2014;123:725-33 pubmed publisher
Huang M, Narita S, Inoue T, Tsuchiya N, Satoh S, Nanjo H, et al. Diet-induced macrophage inhibitory cytokine 1 promotes prostate cancer progression. Endocr Relat Cancer. 2014;21:39-50 pubmed publisher
Foley P, Stegemann B, Ng K, Ramachandran S, Proudler A, Frenneaux M, et al. Growth differentiation factor-15 predicts mortality and morbidity after cardiac resynchronization therapy. Eur Heart J. 2009;30:2749-57 pubmed publisher
Khan S, Ng K, Dhillon O, Kelly D, Quinn P, Squire I, et al. Growth differentiation factor-15 as a prognostic marker in patients with acute myocardial infarction. Eur Heart J. 2009;30:1057-65 pubmed publisher

product information

master code :

MAB957

SKU :

MAB957-100

product name :

Human/Primate GDF-15 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human/Primate GDF-15 Antibody from R&D Systems is a mouse monoclonal antibody to GDF-15. This antibody reacts with human,mouse,primate. The Human/Primate GDF-15 Antibody has been validated for the following applications: Immunoassay Development,Western Blot,ELISA Capture,ELISA Development,ELISA Development (Capture),Luminex Development,Neutralization,In vivo assay,ELISA Capture (Matched Antibody Pair).

target :

GDF-15

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

147627

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human GDF-15, Ala197-Ile308, Accession # Q99988

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Primate

specificity :

Detects human GDF-15 in ELISAs and Western blots. In ELISAs, no cross-reactivity with recombinant human GDF-11, recombinant mouse (rm) GDF-5, rmGDF-6, rmGDF-7, or rmGDF-8 is observed.

gene symbol :

GDF15

accessionNumbers :

Q99988

applications :

Western Blot,ELISA Capture,ELISA Development,ELISA Development (Capture),Luminex Development,Neutralization,In vivo assay,ELISA Capture (Matched Antibody Pair)

USD :

469 USD

alt names :

GDF15, growth differentiation factor 15, growth/differentiation factor 15, Macrophage inhibitory cytokine 1, MIC-1, MIC-1NSAID-activated gene 1 protein, MIC1Prostate differentiation factor, NAG-1, NAG-1NSAID-regulated gene 1 protein, NSAID (nonsteroidal inflammatory drug)-activated protein 1, PDF, PDFGDF-15, PLAB, PLABNRG-1, Placental bone morphogenetic protein, Placental TGF-beta, PTGF-beta, PTGFBPTGF-beta

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage