Human SPARC Antibody | R&D Systems MAB941-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human SPARC Antibody

catalog :

MAB941-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

122511

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 10

Reference
Lin L, Nayak B, Osmulski P, Wang E, Wang C, Valente P, et al. PAI-1 uncouples integrin-β1 from restrain by membrane-bound β-catenin to promote collagen fibril remodeling in obesity-related neoplasms. Cell Rep. 2024;43:114527 pubmed publisher
Sadick J, O Dea M, Hasel P, Dykstra T, Faustin A, Liddelow S. Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer's disease. Neuron. 2022;110:1788-1805.e10 pubmed publisher
Zhou X, Zhang L, Qierang C, Huang M, Yang X, Li L, et al. Investigating the relationship between secreted protein acidic and rich in cysteine expression level and therapeutic efficacy of nab-paclitaxel: a meta-analysis. Transl Cancer Res. 2021;10:876-885 pubmed publisher
Oh Y, Yang S, Liu X, Jana S, Izaddoustdar F, Gao X, et al. Transcriptomic Bioinformatic Analyses of Atria Uncover Involvement of Pathways Related to Strain and Post-translational Modification of Collagen in Increased Atrial Fibrillation Vulnerability in Intensely Exercised Mice. Front Physiol. 2020;11:605671 pubmed publisher
Baird A, Lindsay T, Everett A, Iyemere V, Paterson Y, McClellan A, et al. Osteoblast differentiation of equine induced pluripotent stem cells. Biol Open. 2018;7: pubmed publisher
Mauzo S, Milton D, Prieto V, Torres Cabala C, Wang W, Chakravarti N, et al. Summary of expression of SPARC protein in cutaneous vascular neoplasms and mimickers. Ann Diagn Pathol. 2018;34:151-154 pubmed publisher
Xing P, Zhu Y, Shan L, Chen S, Hao X, Li J. The role of weekly nanoparticle albumin bound paclitaxel monotherapy as second line or later treatment for advanced NSCLC in China. Oncotarget. 2017;8:87442-87454 pubmed publisher
Borazanci E, Millis S, Kimbrough J, Doll N, Von Hoff D, Ramanathan R. Potential actionable targets in appendiceal cancer detected by immunohistochemistry, fluorescent in situ hybridization, and mutational analysis. J Gastrointest Oncol. 2017;8:164-172 pubmed publisher
Moreno M, Ball M, Andrade M, McDermid A, Stanimirovic D. Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells. Glia. 2006;53:845-57 pubmed
Grønborg M, Kristiansen T, Iwahori A, Chang R, Reddy R, Sato N, et al. Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach. Mol Cell Proteomics. 2006;5:157-71 pubmed

product information

master code :

MAB941

SKU :

MAB941-100

product name :

Human SPARC Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human SPARC Antibody from R&D Systems is a mouse monoclonal antibody to SPARC. This antibody reacts with equine,human,mouse. The Human SPARC Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Intracellular Staining by Flow Cytometry,ELISA Development,Immunohistochemistry-Paraffin,Immunocytochemistry,ELISA,CyTOF-ready.

target :

SPARC

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

122511

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human SPARC, Ala18-Ile303, Accession # P09486

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Equine,Human

specificity :

Detects human SPARC/Osteonectin in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse SPARC/Osteonectin is observed.

gene symbol :

SPARC

accessionNumbers :

P09486

applications :

Intracellular Staining by Flow Cytometry,Western Blot,ELISA Development,Immunohistochemistry-Paraffin,Immunocytochemistry,ELISA,Immunohistochemistry,CyTOF-ready

USD :

479 USD

alt names :

Basement-membrane protein 40, BM-40, ONcysteine-rich protein, osteonectin, Secreted protein acidic and rich in cysteine, secreted protein, acidic, cysteine-rich (osteonectin)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage