product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ADAM9 Ectodomain Antibody
catalog :
MAB939
quantity :
500 ug (also 25 ug)
price :
569 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
138537
reactivity :
human, mouse
application :
western blot, neutralization, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 7
Reference
Ueno M, Shiomi T, Mochizuki S, Chijiiwa M, Shimoda M, Kanai Y, et al. ADAM9 is over-expressed in human ovarian clear cell carcinomas and suppresses cisplatin-induced cell death. Cancer Sci. 2018;109:471-482 pubmed publisher
Lin C, Cho C, Bai S, Liu J, Kuo T, Wang L, et al. ADAM9 promotes lung cancer progression through vascular remodeling by VEGFA, ANGPT2, and PLAT. Sci Rep. 2017;7:15108 pubmed publisher
Kossmann C, Annereau M, Thomas Schoemann A, Nicco Overney C, Chereau C, Batteux F, et al. ADAM9 expression promotes an aggressive lung adenocarcinoma phenotype. Tumour Biol. 2017;39:1010428317716077 pubmed publisher
Chiu K, Kuo T, Kuok Q, Lin Y, Hua C, Lin C, et al. ADAM9 enhances CDCP1 protein expression by suppressing miR-218 for lung tumor metastasis. Sci Rep. 2015;5:16426 pubmed publisher
Lin C, Chen H, Huang C, Lai L, Lu T, Tseng G, et al. ADAM9 promotes lung cancer metastases to brain by a plasminogen activator-based pathway. Cancer Res. 2014;74:5229-43 pubmed publisher
Sung S, Kubo H, Shigemura K, Arnold R, Logani S, Wang R, et al. Oxidative stress induces ADAM9 protein expression in human prostate cancer cells. Cancer Res. 2006;66:9519-26 pubmed
Karadag A, Zhou M, Croucher P. ADAM-9 (MDC-9/meltrin-gamma), a member of the a disintegrin and metalloproteinase family, regulates myeloma-cell-induced interleukin-6 production in osteoblasts by direct interaction with the alpha(v)beta5 integrin. Blood. 2006;107:3271-8 pubmed
product information
master code :
MAB939
SKU :
MAB939
product name :
Human ADAM9 Ectodomain Antibody
unit size :
500 ug (also 25 ug)
description :
The Human ADAM9 Ectodomain Antibody from R&D Systems is a mouse monoclonal antibody to ADAM9. This antibody reacts with human,mouse. The Human ADAM9 Ectodomain Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunoprecipitation.
target :
ADAM9
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
138537
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human ADAM9 Ectodomain, Accession # Q13443
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human ADAM9 Ectodomain in Western blots. In Western blots, approximately 10% cross-reactivity with the ectodomain of recombinant mouse ADAM9 is observed and no cross-reactivity with the ectodomain of recombinant human ADAM8, 9, 15, or 17 is observed.
gene symbol :
ADAM9
accessionNumbers :
Q13443
applications :
Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunoprecipitation
USD :
569 USD
alt names :
a disintegrin and metalloproteinase domain 9 (meltrin gamma), ADAM 9, ADAM metallopeptidase domain 9, ADAM metallopeptidase domain 9 (meltrin gamma), Cellular disintegrin-related protein, cone rod dystrophy 9, CORD9, disintegrin and metalloproteinase domain-containing protein 9, EC 3.4.24, EC 3.4.24.-, MCMP, MCMPMDC9KIAA0021Mltng, MDC9, Meltrin gamma, Meltrin-gamma, Metalloprotease/disintegrin/cysteine-rich protein 9, MLTNG, Myeloma cell metalloproteinase
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.