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company name :
R&D Systems
product type :
antibody
product name :
Human VE-Cadherin Antibody
catalog :
MAB9381
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
123413
reactivity :
human, mouse
application :
western blot, immunocytochemistry, flow cytometry
more info or order :
citations: 30
Reference
Liu C, Shen M, Liu Y, Manhas A, Zhao S, Zhang M, et al. CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity. Cell Stem Cell. 2024;31:1760-1776.e9 pubmed publisher
Lietuvninkas L, Baccouche B, Kazlauskas A. The Multi-Kinase Inhibitor RepSox Enforces Barrier Function in the Face of Both VEGF and Cytokines. Biomedicines. 2023;11: pubmed publisher
Chuntharpursat Bon E, Povstyan O, Ludlow M, Carrier D, Debant M, Shi J, et al. PIEZO1 and PECAM1 interact at cell-cell junctions and partner in endothelial force sensing. Commun Biol. 2023;6:358 pubmed publisher
Summer S, Rossmanith E, Pasztorek M, Fiedler C, Gr xf6 ger M, Rauscher S, et al. Mesenchymal stem cells support human vascular endothelial cells to form vascular sprouts in human platelet lysate-based matrices. PLoS ONE. 2022;17:e0278895 pubmed publisher
Raghavan S, Brishti M, COLLIER D, Leo M. Hypoxia induces purinergic receptor signaling to disrupt endothelial barrier function. Front Physiol. 2022;13:1049698 pubmed publisher
Cui X, Stavik B, Thiede B, Sandset P, Kanse S. FSAP Protects against Histone-Mediated Increase in Endothelial Permeability In Vitro. Int J Mol Sci. 2022;23: pubmed publisher
Zhao B, Ni Y, Zhang H, Zhao Y, Li L. Endothelial deletion of TBK1 contributes to BRB dysfunction via CXCR4 phosphorylation suppression. Cell Death Discov. 2022;8:429 pubmed publisher
Olmsted Z, Paluh J. A combined human gastruloid model of cardiogenesis and neurogenesis. iScience. 2022;25:104486 pubmed publisher
Rana D, Kandar A, Salehi Nik N, Inci I, Koopman B, Rouwkema J. Spatiotemporally controlled, aptamers-mediated growth factor release locally manipulates microvasculature formation within engineered tissues. Bioact Mater. 2022;12:71-84 pubmed publisher
Chen H, Yang H, Zhang C, Chen S, Zhao X, Zhu M, et al. Differential Responses of Transplanted Stem Cells to Diseased Environment Unveiled by a Molecular NIR-II Cell Tracker. Research (Wash D C). 2021;2021:9798580 pubmed publisher
Denis K, Cabe J, Danielsson B, Tieu K, Mayer C, Conway D. The LINC complex is required for endothelial cell adhesion and adaptation to shear stress and cyclic stretch. Mol Biol Cell. 2021;:mbcE20110698 pubmed publisher
Propson N, Roy E, Litvinchuk A, Köhl J, Zheng H. Endothelial C3a receptor mediates vascular inflammation and blood-brain barrier permeability during aging. J Clin Invest. 2021;131: pubmed publisher
Daum R, Visser D, Wild C, Kutuzova L, Schneider M, Lorenz G, et al. Fibronectin Adsorption on Electrospun Synthetic Vascular Grafts Attracts Endothelial Progenitor Cells and Promotes Endothelialization in Dynamic In Vitro Culture. Cells. 2020;9: pubmed publisher
Tiemeier G, de Koning R, Wang G, Kostidis S, Rietjens R, Sol W, et al. Lowering the increased intracellular pH of human-induced pluripotent stem cell-derived endothelial cells induces formation of mature Weibel-Palade bodies. Stem Cells Transl Med. 2020;9:758-772 pubmed publisher
Antonelou M, Michaëlsson E, Evans R, Wang C, Henderson S, Walker L, et al. Therapeutic Myeloperoxidase Inhibition Attenuates Neutrophil Activation, ANCA-Mediated Endothelial Damage, and Crescentic GN. J Am Soc Nephrol. 2019;: pubmed publisher
Akk A, Springer L, Yang L, Hamilton Burdess S, Lambris J, Yan H, et al. Complement activation on neutrophils initiates endothelial adhesion and extravasation. Mol Immunol. 2019;114:629-642 pubmed publisher
Kiyan Y, Tkachuk S, Kurselis K, Shushakova N, Stahl K, Dawodu D, et al. Heparanase-2 protects from LPS-mediated endothelial injury by inhibiting TLR4 signalling. Sci Rep. 2019;9:13591 pubmed publisher
Liguori T, Liguori G, Moreira L, Harmsen M. Adipose tissue-derived stromal cells' conditioned medium modulates endothelial-mesenchymal transition induced by IL-1β/TGF-β2 but does not restore endothelial function. Cell Prolif. 2019;52:e12629 pubmed publisher
Neri T, Hiriart E, van Vliet P, Faure E, Norris R, Farhat B, et al. Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis. Nat Commun. 2019;10:1929 pubmed publisher
Gandhi J, Knudsen T, Hill M, Roy B, Bachman L, Pfannkoch Andrews C, et al. Human Fibrinogen for Maintenance and Differentiation of Induced Pluripotent Stem Cells in Two Dimensions and Three Dimensions. Stem Cells Transl Med. 2019;8:512-521 pubmed publisher
Ecker B, Kaur A, Douglass S, Webster M, Almeida F, Marino G, et al. Age-Related Changes in HAPLN1 Increase Lymphatic Permeability and Affect Routes of Melanoma Metastasis. Cancer Discov. 2019;9:82-95 pubmed publisher
Li J, Xing F, Chen F, He L, So K, Liu Y, et al. Functional 3D Human Liver Bud Assembled from MSC-Derived Multiple Liver Cell Lineages. Cell Transplant. 2019;28:510-521 pubmed publisher
Kulhankova K, Kinney K, Stach J, Gourronc F, Grumbach I, Klingelhutz A, et al. The Superantigen Toxic Shock Syndrome Toxin 1 Alters Human Aortic Endothelial Cell Function. Infect Immun. 2018;86: pubmed publisher
Bramley J, Drummond C, Lennemann N, Good C, Kim K, Coyne C. A Three-Dimensional Cell Culture System To Model RNA Virus Infections at the Blood-Brain Barrier. mSphere. 2017;2: pubmed publisher
Colomb F, Wang W, Simpson D, Zafar M, Beynon R, Rhodes J, et al. Galectin-3 interacts with the cell-surface glycoprotein CD146 (MCAM, MUC18) and induces secretion of metastasis-promoting cytokines from vascular endothelial cells. J Biol Chem. 2017;292:8381-8389 pubmed publisher
Odent Grigorescu G, Rosca A, Preda M, Tutuianu R, Simionescu M, Burlacu A. Synergic effects of VEGF-A and SDF-1 on the angiogenic properties of endothelial progenitor cells. J Tissue Eng Regen Med. 2017;11:3241-3252 pubmed publisher
Orecchia P, Conte R, Balza E, Pietra G, Mingari M, Carnemolla B. Targeting Syndecan-1, a molecule implicated in the process of vasculogenic mimicry, enhances the therapeutic efficacy of the L19-IL2 immunocytokine in human melanoma xenografts. Oncotarget. 2015;6:37426-42 pubmed publisher
Das A, Lenz S, Awojoodu A, Botchwey E. Abluminal stimulation of sphingosine 1-phosphate receptors 1 and 3 promotes and stabilizes endothelial sprout formation. Tissue Eng Part A. 2015;21:202-13 pubmed publisher
Lindsley R, Gill J, Murphy T, Langer E, Cai M, Mashayekhi M, et al. Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs. Cell Stem Cell. 2008;3:55-68 pubmed publisher
Rajesh M, Mukhopadhyay P, Bátkai S, Haskó G, Liaudet L, Drel V, et al. Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption. Am J Physiol Heart Circ Physiol. 2007;293:H610-9 pubmed
product information
master code :
MAB9381
SKU :
MAB9381
product name :
Human VE-Cadherin Antibody
unit size :
100 ug (also 25 ug)
description :
The Human VE-Cadherin Antibody from R&D Systems is a mouse monoclonal antibody to VE-Cadherin. This antibody reacts with human,mouse. The Human VE-Cadherin Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Flow Cytometry,CyTOF-ready.
target :
VE-Cadherin
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
123413
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human VE-Cadherin, Asp48-Gln593, Accession # P33151
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human VE-Cadherin in Western blots. In Western blots, 25% cross-reactivity with recombinant mouse VE-Cadherin and no cross-reactivity with recombinant human (rh) Cadherin-17 or rhP-Cadherin is observed.
gene symbol :
CDH5
top caption :
Detection of Human VE-Cadherin antibody by Western Blot.
accessionNumbers :
P33151
applications :
Flow Cytometry,Immunocytochemistry,Western Blot,CyTOF-ready
USD :
519 USD
alt names :
7B4, 7B4 antigen, cadherin 5, type 2 (vascular endothelium), cadherin 5, type 2, VE-cadherin (vascular epithelium), cadherin-5, CD144, CD144 antigen, CDH5, endothelial-specific cadherin, FLJ17376, Vascular endothelial cadherin, VE-cadherin, VECadherin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.