Human/Rat/Hamster ACE-2 Antibody | R&D Systems MAB9331 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Rat/Hamster ACE-2 Antibody

catalog :

MAB9331

quantity :

100 ug (also 25 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

171608

reactivity :

Syrian golden hamster

application :

western blot, immunohistochemistry, neutralization, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Bejoy J, Williams C, Cole H, Manzoor S, Davoodi P, Battaile J, et al. Effects of spike proteins on angiotensin converting enzyme 2 (ACE2). Arch Biochem Biophys. 2023;748:109769 pubmed publisher
Grimm L, Onyeukwu C, Kenny G, Parent D, Fu J, Dhingra S, et al. Immune Dysregulation in Acute SARS-CoV-2 Infection. Pathog Immun. 2022;7:143-170 pubmed publisher
Lindskog C, M xe9 ar L, Virhammar J, F xe4 llmar D, Kumlien E, Hesselager G, et al. Protein Expression Profile of ACE2 in the Normal and COVID-19-Affected Human Brain. J Proteome Res. 2022;21:2137-2145 pubmed publisher
Yamaguchi T, Hoshizaki M, Minato T, Nirasawa S, Asaka M, Niiyama M, et al. ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury. Nat Commun. 2021;12:6791 pubmed publisher
Asaka M, Utsumi D, Kamada H, Nagata S, Nakachi Y, Yamaguchi T, et al. Highly susceptible SARS-CoV-2 model in CAG promoter-driven hACE2-transgenic mice. JCI Insight. 2021;6: pubmed publisher
Sherman E, Emmer B. ACE2 protein expression within isogenic cell lines is heterogeneous and associated with distinct transcriptomes. Sci Rep. 2021;11:15900 pubmed publisher
Han D, Penn Nicholson A, Cho M. Identification of critical determinants on ACE2 for SARS-CoV entry and development of a potent entry inhibitor. Virology. 2006;350:15-25 pubmed
Jiang Y, Xu J, Zhou C, Wu Z, Zhong S, Liu J, et al. Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome. Am J Respir Crit Care Med. 2005;171:850-7 pubmed

product information

master code :

MAB9331

SKU :

MAB9331

product name :

Human/Rat/Hamster ACE-2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Rat/Hamster ACE-2 Antibody from R&D Systems is a mouse monoclonal antibody to ACE-2. This antibody reacts with hamster,human,mouse,rat. The Human/Rat/Hamster ACE-2 Antibody has been validated for the following applications: ELISA Capture,Immunohistochemistry,Blocking/Neutralizing,Flow Cytometry,Western Blot,Immunoprecipitation.

target :

ACE-2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

171608

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human ACE-2, Gln18-Ser740 (predicted), Accession # Q9BYF1

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Hamster,Human,Mouse,Rat

specificity :

Detects recombinant human ACE-2 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human ACE-1 or recombinant mouse ACE-1 is observed.

gene symbol :

ACE2

top caption :

Detection of Human ACE-2 antibody by Western Blot.

accessionNumbers :

Q9BYF1

applications :

Immunohistochemistry,Blocking/Neutralizing,Flow Cytometry,Western Blot,Immunoprecipitation

USD :

459 USD

alt names :

ACE2, ACEH, ACEHangiotensin I converting enzyme 2, ACE-related carboxypeptidase, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2, angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog, DKFZp434A014, EC 3.4.17, EC 3.4.17.23, Metalloprotease MPROT15

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage