product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TACE/ADAM17 Ectodomain Antibody
catalog :
MAB9302
quantity :
500 ug (also 25 ug)
price :
569 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
111623
reactivity :
human
application :
western blot, immunoprecipitation, flow cytometry
more info or order :
R&D Systems product webpage
citations: 3
Reference
Jing Y, Ni Z, Wu J, Higgins L, Markowski T, Kaufman D, et al. Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells. PLoS ONE. 2015;10:e0121788 pubmed publisher
DeRycke M, Pambuccian S, Gilks C, Kalloger S, Ghidouche A, Lopez M, et al. Nectin 4 overexpression in ovarian cancer tissues and serum: potential role as a serum biomarker. Am J Clin Pathol. 2010;134:835-45 pubmed publisher
Von Tresckow B, Kallen K, Von Strandmann E, Borchmann P, Lange H, Engert A, et al. Depletion of cellular cholesterol and lipid rafts increases shedding of CD30. J Immunol. 2004;172:4324-31 pubmed
product information
master code :
MAB9302
SKU :
MAB9302
product name :
Human TACE/ADAM17 Ectodomain Antibody
unit size :
500 ug (also 25 ug)
description :
The Human TACE/ADAM17 Ectodomain Antibody from R&D Systems is a mouse monoclonal antibody to TACE/ADAM17. This antibody reacts with human. The Human TACE/ADAM17 Ectodomain Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunoprecipitation.
target :
TACE/ADAM17
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
111623
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Insect ovarian cell line T. ni -derived recombinant human TACE/ADAM17, Pro18-Asn671 (predicted), Accession # P78536
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human TACE/ADAM17 Ectodomain in direct ELISAs and Western blots. In direct ELISAs, less than 2% cross-reactivity with recombinant human ADAM8, 9, 15, and recombinant mouse ADAM10 is observed.
gene symbol :
ADAM17
top caption :
Detection of Human TACE/ADAM17 by Flow Cytometry
accessionNumbers :
P78536
applications :
Flow Cytometry,Western Blot,Immunoprecipitation
USD :
569 USD
alt names :
ADAM 17, ADAM metallopeptidase domain 17, ADAM metallopeptidase domain 18, ADAM17, ADAM18, CD156b, CD156b antigen, CSVP, disintegrin and metalloproteinase domain-containing protein 17, EC 3.4.24.86, MGC71942, Snake venom-like protease, TACEcSVP, TNF-alpha convertase, TNF-alpha converting enzyme, TNF-alpha-converting enzyme, tumor necrosis factor, alpha, converting enzyme
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.