product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human Angiopoietin-1 Antibody
catalog :
MAB923-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
171718
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 10
Reference
Harary S xf8 ndergaard R, Drozd H xf8 jgaard L, Haack S xf8 rensen M, Hoeeg C, M xf8 nsted Johansen E, Follin B, et al. Investigating the paracrine and juxtacrine abilities of adipose-derived stromal cells in angiogenesis triple cell co-cultures. Stem Cell Res. 2024;77:103417 pubmed publisher
Zheng C, Toth J, Bigwarfe T, MacDougall M, Jerath K, Bovat K, et al. Non-neutralizing antibodies increase endogenous circulating Ang1 levels. MAbs. 2018;10:1260-1268 pubmed publisher
Kato K, Diéguez Hurtado R, Park D, Hong S, Kato Azuma S, Adams S, et al. Pulmonary pericytes regulate lung morphogenesis. Nat Commun. 2018;9:2448 pubmed publisher
Chan W, Ismail H, Mayaki D, Sanchez V, Tiedemann K, Davis E, et al. Fibulin-5 Regulates Angiopoietin-1/Tie-2 Receptor Signaling in Endothelial Cells. PLoS ONE. 2016;11:e0156994 pubmed publisher
Scheuer W, Thomas M, Hanke P, Sam J, Osl F, Weininger D, et al. Anti-tumoral, anti-angiogenic and anti-metastatic efficacy of a tetravalent bispecific antibody (TAvi6) targeting VEGF-A and angiopoietin-2. MAbs. 2016;8:562-73 pubmed publisher
Khairoun M, van den Heuvel M, van den Berg B, Sorop O, de Boer R, van Ditzhuijzen N, et al. Early systemic microvascular damage in pigs with atherogenic diabetes mellitus coincides with renal angiopoietin dysbalance. PLoS ONE. 2015;10:e0121555 pubmed publisher
Cheng C, Hou H, Jhuang J, Lin C, Chen C, Tang J, et al. High bone marrow angiopoietin-1 expression is an independent poor prognostic factor for survival in patients with myelodysplastic syndromes. Br J Cancer. 2011;105:975-82 pubmed publisher
Dallabrida S, Ismail N, Pravda E, Parodi E, Dickie R, Durand E, et al. Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy. FASEB J. 2008;22:3010-23 pubmed publisher
Mofarrahi M, Nouh T, Qureshi S, Guillot L, Mayaki D, Hussain S. Regulation of angiopoietin expression by bacterial lipopolysaccharide. Am J Physiol Lung Cell Mol Physiol. 2008;294:L955-63 pubmed publisher
Hashiramoto A, Sakai C, Yoshida K, Tsumiyama K, Miura Y, Shiozawa K, et al. Angiopoietin 1 directly induces destruction of the rheumatoid joint by cooperative, but independent, signaling via ERK/MAPK and phosphatidylinositol 3-kinase/Akt. Arthritis Rheum. 2007;56:2170-9 pubmed
product information
master code :
MAB923
SKU :
MAB923-100
product name :
Human Angiopoietin-1 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human Angiopoietin-1 Antibody from R&D Systems is a mouse monoclonal antibody to Angiopoietin-1. This antibody reacts with human,mouse,porcine,rat. The Human Angiopoietin-1 Antibody has been validated for the following applications: Neutralization,ELISA Development,Immunoprecipitation,Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
Angiopoietin-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
171718
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Angiopoietin-1, Ser20-Phe498, Accession # Q15389
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Porcine,Rat
specificity :
Detects human Angiopoietin-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Angiopoietin-2, recombinant mouse Angiopoietin-like 3, rhAngiopoietin-4, or rhAngiopoietin-like 7 is observed.
gene symbol :
ANGPT1
top caption :
Angiopoietin-1 antibody in Human Prostate Cancer Tissue by Immunohistochemistry (IHC-P).
accessionNumbers :
Q15389
applications :
Neutralization,ELISA Development,Immunoprecipitation,Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
469 USD
alt names :
AGP1, AGPT, Ang1, ANG-1, angiopoietin 1, angiopoietin-1, ANGPT1, KIAA0003
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.