product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Lactate Dehydrogenase B/LDHB Antibody
catalog :
MAB9205-100
quantity :
100 ug (also 25 ug)
price :
449 USD
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
2057D
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2a
Deng H, Gao Y, Trappetti V, Hertig D, Karatkevich D, Losmanová T, et al. Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cell Mol Life Sci. 2022;79:445 pubmed publisher
Frank A, Vandiver F, McFadden D. Forward genetic screens identify mechanisms of resistance to small molecule lactate dehydrogenase inhibitors. bioRxiv. 2023;: pubmed publisher
San Millan I, Martinez J, Pickard S, Yu H, Hirsch F, Rivard C, et al. Role of Lactate in the Regulation of Transcriptional Activity of Breast Cancer-Related Genes and Epithelial-to-Mesenchymal Transition Proteins: A Compassion of MCF7 and MDA-MB-231 Cancer Cell Lines. bioRxiv. 2023;: pubmed publisher
La Montagna M, Shi L, Magee P, Sahoo S, Fassan M, Garofalo M. AMPKα loss promotes KRAS-mediated lung tumorigenesis. Cell Death Differ. 2021;: pubmed publisher
Albanesi J, Noguera N, Banella C, Colangelo T, De Marinis E, Leone S, et al. Transcriptional and Metabolic Dissection of ATRA-Induced Granulocytic Differentiation in NB4 Acute Promyelocytic Leukemia Cells. Cells. 2020;9: pubmed publisher
product information
master code :
MAB9205
SKU :
MAB9205-100
product name :
Human Lactate Dehydrogenase B/LDHB Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Lactate Dehydrogenase B/LDHB Antibody from R&D Systems is a rabbit monoclonal antibody to Lactate Dehydrogenase B. This antibody reacts with human. The Human Lactate Dehydrogenase B/LDHB Antibody has been validated for the following applications: Simple Western,Western Blot,Immunohistochemistry,Intracellular Staining by Flow Cytometry,Immunocytochemistry,Knockout Validated.
target :
Lactate Dehydrogenase B/LDHB
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
2057D
conjugate :
Unconjugated
host :
Rabbit
immunogen :
E. coli -derived recombinant human LDHB, Met1-Val93, Accession # P07195
isotype :
IgG
purity :
Protein A or G purified from cell culture supernatant
species :
Human
specificity :
Detects human LDHB in direct ELISAs and Western blots.
Antibody validation :
Knockout/Knockdown
top caption :
Detection of Human Lactate Dehydrogenase B/LDHB antibody by Western Blot.
accessionNumbers :
P07195
applications :
Simple Western,Western Blot,Immunohistochemistry,Intracellular Staining by Flow Cytometry,Immunocytochemistry,Knockout Validated
extended description :
Recombinant Monoclonal Antibody.
USD :
449 USD
product details :
Recombinant Monoclonal Antibody.
alt names :
EC 1.1.1, EC 1.1.1.27, Epididymis Secretory Protein Li 281, HEL-S-281, lactate dehydrogenase B, LDH heart subunit, LDHB, LDH-B, LDHBD, LDH-H, L-lactate dehydrogenase B chain, Renal Carcinoma Antigen NY-REN-46, TRG-5
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.