Human MMP-12 Catalytic Domain Antibody | R&D Systems MAB919 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human MMP-12 Catalytic Domain Antibody

catalog :

MAB919

quantity :

500 ug (also 25 ug)

price :

569 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

82902

reactivity :

human

application :

western blot, immunohistochemistry, neutralization, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 10 ug/ml; loading ...; fig 5j	Di Gregoli K, Somerville M, Bianco R, Thomas A, Frankow A, Newby A, et al. Galectin-3 Identifies a Subset of Macrophages With a Potential Beneficial Role in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2020;40:1491-1509 pubmed publisher
	M x142 ynarczyk G, Tokarzewicz A, Gudowska Sawczuk M, Mroczko B, Nov xe1 k V, Nov xe1 k A, et al. MMP-14 Exhibits Greater Expression, Content and Activity Compared to MMP-15 in Human Renal Carcinoma. Int J Mol Sci. 2024;25: pubmed publisher
	Asakage M, Usui Y, Nezu N, Shimizu H, Tsubota K, Umazume K, et al. Comprehensive Gene Analysis of IgG4-Related Ophthalmic Disease Using RNA Sequencing. J Clin Med. 2020;9: pubmed publisher
	Beltrami Moreira M, Vromman A, Sukhova G, Folco E, Libby P. Redundancy of IL-1 Isoform Signaling and Its Implications for Arterial Remodeling. PLoS ONE. 2016;11:e0152474 pubmed publisher
	Founds S, Zeng X, Lykins D, Roberts J. Developing Potential Candidates of Preclinical Preeclampsia. Int J Mol Sci. 2015;16:27208-27 pubmed publisher
	Wang P, Chen S, Hung W, Paul C, Zhu F, Guan P, et al. Fluid shear promotes chondrosarcoma cell invasion by activating matrix metalloproteinase 12 via IGF-2 and VEGF signaling pathways. Oncogene. 2015;34:4558-69 pubmed publisher
	Kong M, Gaggar A, Li Y, Winkler M, Blalock J, Clancy J. Matrix metalloproteinase activity in pediatric acute lung injury. Int J Med Sci. 2009;6:9-17 pubmed
	Dean R, Cox J, Bellac C, Doucet A, Starr A, Overall C. Macrophage-specific metalloelastase (MMP-12) truncates and inactivates ELR+ CXC chemokines and generates CCL2, -7, -8, and -13 antagonists: potential role of the macrophage in terminating polymorphonuclear leukocyte influx. Blood. 2008;112:3455-64 pubmed publisher
	Coury F, Annels N, Rivollier A, Olsson S, Santoro A, Speziani C, et al. Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion. Nat Med. 2008;14:81-7 pubmed
	Rust R, Kluiver J, Visser L, Harms G, Blokzijl T, Kamps W, et al. Gene expression analysis of dendritic/Langerhans cells and Langerhans cell histiocytosis. J Pathol. 2006;209:474-83 pubmed
	Lavigne M, Thakker P, Gunn J, Wong A, Miyashiro J, Wasserman A, et al. Human bronchial epithelial cells express and secrete MMP-12. Biochem Biophys Res Commun. 2004;324:534-46 pubmed

product information

master code :

MAB919

SKU :

MAB919

product name :

Human MMP-12 Catalytic Domain Antibody

unit size :

500 ug (also 25 ug)

description :

The Human MMP-12 Catalytic Domain Antibody from R&D Systems is a mouse monoclonal antibody to MMP-12. This antibody reacts with human. The Human MMP-12 Catalytic Domain Antibody has been validated for the following applications: Western Blot,Flow Cytometry,Immunoprecipitation,Neutralization,Immunohistochemistry,Immunoaffinity Purification.

target :

MMP-12

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

82902

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human MMP-12

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human MMP-12 Catalytic Domain. Does not recognize the C-terminal hemopexin-like domain of human MMP-12. Does not cross-react with recombinant human MMP-1, -2, -3, -7, -8, -9, -10, or -13.

gene symbol :

MMP12

applications :

Western Blot,Flow Cytometry,Immunoprecipitation,Neutralization,Immunohistochemistry,Immunoaffinity Purification

USD :

569 USD

alt names :

EC 3.4.24, hME, HMEEC 3.4.24.65, Macrophage elastase, macrophage metalloelastase, matrix metallopeptidase 12 (macrophage elastase), matrix metalloproteinase 12 (macrophage elastase), Matrix metalloproteinase-12, ME, MGC138506, MME, MMP12, MMP-12

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage