product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human MMP-14/MT1-MMP Antibody
catalog :
MAB918
quantity :
500 ug (also 25 ug)
price :
569 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5H2
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
R&D Systems product webpage
citations: 3
Reference
Kaimal R, Aljumaily R, Tressel S, Pradhan R, Covic L, Kuliopulos A, et al. Selective blockade of matrix metalloprotease-14 with a monoclonal antibody abrogates invasion, angiogenesis, and tumor growth in ovarian cancer. Cancer Res. 2013;73:2457-2467 pubmed publisher
Nascimento C, de Siqueira A, Pinheiro J, Freitas V, Jaeger R. Laminin-111 derived peptides AG73 and C16 regulate invadopodia activity of a human adenoid cystic carcinoma cell line. Exp Cell Res. 2011;317:2562-72 pubmed publisher
Shirvaikar N, Marquez Curtis L, Ratajczak M, Janowska Wieczorek A. Hyaluronic acid and thrombin upregulate MT1-MMP through PI3K and Rac-1 signaling and prime the homing-related responses of cord blood hematopoietic stem/progenitor cells. Stem Cells Dev. 2011;20:19-30 pubmed publisher
product information
master code :
MAB918
SKU :
MAB918
product name :
Human MMP-14/MT1-MMP Antibody
unit size :
500 ug (also 25 ug)
description :
The Human MMP-14/MT1-MMP Antibody from R&D Systems is a mouse monoclonal antibody to MMP-14/MT1-MMP. This antibody reacts with human. The Human MMP-14/MT1-MMP Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Immunohistochemistry,Immunoprecipitation.
target :
MMP-14/MT1-MMP
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in TBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
5H2
conjugate :
Unconjugated
host :
Mouse
immunogen :
Human MMP-14 synthetic peptide, AYIREGHEKQA, Accession # P50281
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects recombinant human (rh) MMP-14 in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) MMP-1, -2, -7, -8, -9, -10, -12, -13 or the catalytic domains of rhMMP-15 and -16.
gene symbol :
MMP14
top caption :
Detection of Human MMP-14/MT1-MMP antibody by Western Blot.
accessionNumbers :
P50281
applications :
Western Blot,Immunocytochemistry,Immunohistochemistry,Immunoprecipitation
USD :
569 USD
alt names :
EC 3.4.24, EC 3.4.24.80, matrix metallopeptidase 14 (membrane-inserted), matrix metalloproteinase 14 (membrane-inserted), matrix metalloproteinase-14, membrane type 1 metalloprotease, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, MMP14, MMP-14, MMP-X1, MT1MMP, MT1-MMP, MT1-MMPMTMMP1, MT-MMP 1, MT-MMP1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.