product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human MMP-15/MT2-MMP Antibody
catalog :
MAB9161
quantity :
500 ug (also 25 ug)
price :
549 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
130522
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Reference
Fakhari S, Jalili A, Nikkhoo B, Ghaderi B, Boshagh M, Mirzaie S, et al. MT2-MMP is differentially expressed in multiple myeloma cells and mediates their growth and progression. Cell Signal. 2022;92:110248 pubmed publisher
Thome I, Lacle R, Voß A, Bortolussi G, Pantazis G, Schmidt A, et al. Neoplastic Cells are the Major Source of MT-MMPs in IDH1-Mutant Glioma, Thus Enhancing Tumor-Cell Intrinsic Brain Infiltration. Cancers (Basel). 2020;12: pubmed publisher
Kaitu u Lino T, Palmer K, Tuohey L, Ye L, Tong S. MMP-15 is upregulated in preeclampsia, but does not cleave endoglin to produce soluble endoglin. PLoS ONE. 2012;7:e39864 pubmed publisher
product information
master code :
MAB9161
SKU :
MAB9161
product name :
Human MMP-15/MT2-MMP Antibody
unit size :
500 ug (also 25 ug)
description :
The Human MMP-15/MT2-MMP Antibody from R&D Systems is a mouse monoclonal antibody to MMP-15/MT2-MMP. This antibody reacts with human. The Human MMP-15/MT2-MMP Antibody has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Western Blot,Intracellular Staining by Flow Cytometry,CyTOF-ready.
target :
MMP-15/MT2-MMP
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
130522
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human MMP-15, aa 132-625
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human MMP-15/MT2-MMP in direct ELISAs and Western blots. Does not detect the catalytic domain of E. coli -expressed recombinant human MMP-15 (aa 132-304).
gene symbol :
MMP15
applications :
Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Western Blot,Intracellular Staining by Flow Cytometry,CyTOF-ready
USD :
549 USD
alt names :
EC 3.4.24, EC 3.4.24.-, EC 3.4.24.80, matrix metallopeptidase 15 (membrane-inserted), matrix metalloproteinase 15 (membrane-inserted), Membrane-type matrix metalloproteinase 2, Membrane-type-2 matrix metalloproteinase, MMP15, MMP-15, MT2-MMP, MT2-MMPMT2MMP, MTMMP2MT-MMP 2, SMCP-2matrix metalloproteinase-15
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.