product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human MMP-9 Antibody
catalog :
MAB911
quantity :
200 ug (also 25 ug)
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4H3
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 26
Reference
Fern xe1 ndez Vallone V, Borzone F, Martinez L, Giorello M, Choi H, Dimase F, et al. Spontaneous Osteoclastogenesis, a risk factor for bone metastasis in advanced luminal A-type breast cancer patients. Front Oncol. 2023;13:1073793 pubmed publisher
Mlakar L, Garrett S, Watanabe T, Sanderson M, Nishimoto T, Heywood J, et al. Ameliorating Fibrosis in Murine and Human Tissues with END55, an Endostatin-Derived Fusion Protein Made in Plants. Biomedicines. 2022;10: pubmed publisher
Brockmueller A, Mueller A, Shayan P, Shakibaei M. β1-Integrin plays a major role in resveratrol-mediated anti-invasion effects in the CRC microenvironment. Front Pharmacol. 2022;13:978625 pubmed publisher
Lindgren M, Rask G, Jonsson J, Berglund A, Lundin C, Jonsson P, et al. Type IV Collagen in Human Colorectal Liver Metastases-Cellular Origin and a Circulating Biomarker. Cancers (Basel). 2022;14: pubmed publisher
Sullivan G, Galdi P, Borbye Lorenzen N, Stoye D, Lamb G, Evans M, et al. Preterm Birth Is Associated With Immune Dysregulation Which Persists in Infants Exposed to Histologic Chorioamnionitis. Front Immunol. 2021;12:722489 pubmed publisher
Hou T, Wu S, Kau H, Tsai C. JNK and p38 Inhibitors Prevent Transforming Growth Factor-β1-Induced Myofibroblast Transdifferentiation in Human Graves' Orbital Fibroblasts. Int J Mol Sci. 2021;22: pubmed publisher
Walsh S, Worrell J, Fabre A, Hinz B, Kane R, Keane M. Novel differences in gene expression and functional capabilities of myofibroblast populations in idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol. 2018;315:L697-L710 pubmed publisher
Cortes A, Gonsalez S, Rioja L, Oliveira S, Santos A, Prieto M, et al. Protective outcomes of low-dose doxycycline on renal function of Wistar rats subjected to acute ischemia/reperfusion injury. Biochim Biophys Acta Mol Basis Dis. 2018;1864:102-114 pubmed publisher
Orgaz J, Pandya P, Dalmeida R, Karagiannis P, Sanchez Laorden B, Viros A, et al. Diverse matrix metalloproteinase functions regulate cancer amoeboid migration. Nat Commun. 2014;5:4255 pubmed publisher
Sohal S, Soltani A, Reid D, Ward C, Wills K, Muller H, et al. A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial-mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study. Int J Chron Obstruct Pulmon Dis. 2014;9:533-42 pubmed publisher
Shakibaei M, Mobasheri A, Lueders C, Büsch F, Shayan P, Goel A. Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-?B and Src protein kinase signaling pathways. PLoS ONE. 2013;8:e57218 pubmed publisher
Shakibaei M, Allaway D, Nebrich S, Mobasheri A. Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1?-Induced NF-?B Activation in Canine Articular Chondrocytes. Evid Based Complement Alternat Med. 2012;2012:509383 pubmed publisher
Lichtenauer M, Mildner M, Hoetzenecker K, Zimmermann M, Podesser B, Sipos W, et al. Secretome of apoptotic peripheral blood cells (APOSEC) confers cytoprotection to cardiomyocytes and inhibits tissue remodelling after acute myocardial infarction: a preclinical study. Basic Res Cardiol. 2011;106:1283-97 pubmed publisher
Ruehl M, Muche M, Freise C, Erben U, Neumann U, Schuppan D, et al. Hydroxyproline-containing collagen analogs trigger the release and activation of collagen-sequestered proMMP-2 by competition with prodomain-derived peptide P33-42. Fibrogenesis Tissue Repair. 2011;4:1 pubmed publisher
Li M, Hou X, Shao J, Tang C, Li D. The DSCs-expressed CD82 controls the invasiveness of trophoblast cells via integrinbeta1/MAPK/MAPK3/1 signaling pathway in human first-trimester pregnancy. Biol Reprod. 2010;82:968-79 pubmed publisher
Teles R, Teles R, Amadeu T, Moura D, Mendonça Lima L, Ferreira H, et al. High matrix metalloproteinase production correlates with immune activation and leukocyte migration in leprosy reactional lesions. Infect Immun. 2010;78:1012-21 pubmed publisher
Lucio Eterovic A, Piao Y, de Groot J. Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy. Clin Cancer Res. 2009;15:4589-99 pubmed publisher
Madsen E, Bruun J, Skogstrand K, Hougaard D, Christiansen T, Richelsen B. Long-term weight loss decreases the nontraditional cardiovascular risk factors interleukin-18 and matrix metalloproteinase-9 in obese subjects. Metabolism. 2009;58:946-53 pubmed publisher
Kong M, Gaggar A, Li Y, Winkler M, Blalock J, Clancy J. Matrix metalloproteinase activity in pediatric acute lung injury. Int J Med Sci. 2009;6:9-17 pubmed
Ohlund D, Ardnor B, Oman M, Naredi P, Sund M. Expression pattern and circulating levels of endostatin in patients with pancreas cancer. Int J Cancer. 2008;122:2805-10 pubmed publisher
Gupta K, Shukla M, Cowland J, Malemud C, Haqqi T. Neutrophil gelatinase-associated lipocalin is expressed in osteoarthritis and forms a complex with matrix metalloproteinase 9. Arthritis Rheum. 2007;56:3326-35 pubmed
Kleinman M, Greives M, Churgin S, Blechman K, Chang E, Ceradini D, et al. Hypoxia-induced mediators of stem/progenitor cell trafficking are increased in children with hemangioma. Arterioscler Thromb Vasc Biol. 2007;27:2664-70 pubmed
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product information
brand :
R&D Systems
master code :
MAB911
SKU :
MAB911
product name :
Human MMP-9 Antibody
unit size :
200 ug (also 25 ug)
seo description :
The Human MMP-9 Antibody from R&D Systems is a mouse monoclonal antibody to MMP-9. This antibody reacts with human. The Human MMP-9 Antibody has been validated for the following applications: Immunohistochemistry,Cell-based ELISA,Luminex Development,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-reported.
target :
MMP-9
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
4H3
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 2 ug/mL, Immunohistochemistry 25-100 ug/mL, Immunoprecipitation 25 ug/mL, CyTOF-reported
host :
Mouse
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant human MMP-9
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human MMP-9 in Western blots. In Western blots, reactivity with the pro (92 kDa), active (82 kDa), and C-terminal truncated (65 kDa) forms of recombinant human (rh) MMP-9 is observed. Also in Western blots, 20% cross-reactivity with rhMMP-2, 5% cross-reactivity with rhMMP-1, and no cross-reactivity with rhMMP-3, -7, -8, -10, -12, or -13 is observed.
gene symbol :
MMP9
top caption :
Detection of Human MMP-9 antibody by Western Blot.
applications :
CyTOF-reported,Cell-based ELISA,Luminex Development,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
499 USD
alt names :
92 kDa gelatinase, 92 kDa type IV collagenase, CLG4B, EC 3.4.24, EC 3.4.24.35, Gelatinase B, GELB, macrophage gelatinase, MANDP2, matrix metallopeptidase 9, matrix metalloproteinase 9, matrix metalloproteinase-9, MMP9, MMP-9, type V collagenase
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.