product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human MMP-10 Antibody
catalog :
MAB910-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
110304
reactivity :
human
application :
western blot, immunohistochemistry
more info or order :
citations: 9
Reference
Li L, Jiao L, Feng D, Yuan Y, Yang X, Li J, et al. Human apical-out nasal organoids reveal an essential role of matrix metalloproteinases in airway epithelial differentiation. Nat Commun. 2024;15:143 pubmed publisher
Kudelski J, M x142 ynarczyk G, Gudowska Sawczuk M, Mroczko B, Darewicz B, Bruczko Goralewska M, et al. Higher Content but Not Activity of Stromelysin-2 (MMP-10) in Comparison to Stromelysin-1 (MMP-3) in Human Renal Carcinoma. Int J Environ Res Public Health. 2022;19: pubmed publisher
Kudelski J, Młynarczyk G, Gudowska Sawczuk M, Mroczko B, Darewicz B, Bruczko Goralewska M, et al. Enhanced Expression but Decreased Specific Activity of Matrix Metalloproteinase 10 (MMP-10) in Comparison with Matrix Metalloproteinase 3 (MMP-3) in Human Urinary Bladder Carcinoma. J Clin Med. 2021;10: pubmed publisher
Luo F, Tran A, Xin L, Sanapala C, Lang B, Silver J, et al. Modulation of proteoglycan receptor PTPσ enhances MMP-2 activity to promote recovery from multiple sclerosis. Nat Commun. 2018;9:4126 pubmed publisher
Puram S, Tirosh I, Parikh A, Patel A, Yizhak K, Gillespie S, et al. Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer. Cell. 2017;171:1611-1624.e24 pubmed publisher
Crowley J, Strle K, Drouin E, Pianta A, Arvikar S, Wang Q, et al. Matrix metalloproteinase-10 is a target of T and B cell responses that correlate with synovial pathology in patients with antibiotic-refractory Lyme arthritis. J Autoimmun. 2016;69:24-37 pubmed publisher
Du X, Lin B, Wang Q, Li H, Ingalla E, Tien J, et al. MMP-1 and Pro-MMP-10 as potential urinary pharmacodynamic biomarkers of FGFR3-targeted therapy in patients with bladder cancer. Clin Cancer Res. 2014;20:6324-35 pubmed publisher
Kong M, Gaggar A, Li Y, Winkler M, Blalock J, Clancy J. Matrix metalloproteinase activity in pediatric acute lung injury. Int J Med Sci. 2009;6:9-17 pubmed
Schnickmann S, Camacho Trullio D, Bissinger M, Eils R, Angel P, Schirmacher P, et al. AP-1-controlled hepatocyte growth factor activation promotes keratinocyte migration via CEACAM1 and urokinase plasminogen activator/urokinase plasminogen receptor. J Invest Dermatol. 2009;129:1140-8 pubmed publisher
product information
master code :
MAB910
SKU :
MAB910-100
product name :
Human MMP-10 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human MMP-10 Antibody from R&D Systems is a mouse monoclonal antibody to MMP-10. This antibody reacts with human. The Human MMP-10 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry.
target :
MMP-10
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
110304
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human MMP-10, Tyr18-Cys476, Accession # P09238
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human MMP-10 in Western blots. Does not cross-react with recombinant human MMP-1, -2, -3, -7, -8, -9, -12, or -13.
gene symbol :
MMP10
top caption :
MMP-10 antibody in Human Colon Cancer Tissue by Immunohistochemistry (IHC-P).
accessionNumbers :
P09238
applications :
Western Blot,Immunohistochemistry
USD :
469 USD
alt names :
EC 3.4.24, EC 3.4.24.22, matrix metallopeptidase 10 (stromelysin 2), matrix metalloprotease 10, matrix metalloproteinase 10 (stromelysin 2), Matrix metalloproteinase-10, MMP10, MMP-10, SL-2, STMY2stromelysin-2, stromelysin 2, transin 2, transin-2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.