Mouse PD-L1/B7-H1 Antibody | R&D Systems MAB90781-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse PD-L1/B7-H1 Antibody

catalog :

MAB90781-100

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

2096C

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 12

Reference
Cao Y, Ye Q, Ma M, She Q. Enhanced bypass of PD-L1 translation reduces the therapeutic response to mTOR kinase inhibitors. Cell Rep. 2023;42:112764 pubmed publisher
Shrestha M, Wang D, Ben David Y, Zacksenhaus E. CDK4/6 inhibitors and the pRB-E2F1 axis suppress PVR and PD-L1 expression in triple-negative breast cancer. Oncogenesis. 2023;12:29 pubmed publisher
Zhang S, You X, Xu T, Chen Q, Li H, Dou L, et al. PD-L1 induction via the MEK-JNK-AP1 axis by a neddylation inhibitor promotes cancer-associated immunosuppression. Cell Death Dis. 2022;13:844 pubmed publisher
Hiatt J, Sandborg H, Garrison S, Arnold H, Liao S, Norton J, et al. Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing. Clin Cancer Res. 2022;28:4551-4564 pubmed publisher
Wang X, Wang K, Yu M, Velluto D, Hong X, Wang B, et al. Engineered immunomodulatory accessory cells improve experimental allogeneic islet transplantation without immunosuppression. Sci Adv. 2022;8:eabn0071 pubmed publisher
Skibbe K, Brethack A, Sünderhauf A, Ragab M, Raschdorf A, Hicken M, et al. Colorectal Cancer Progression Is Potently Reduced by a Glucose-Free, High-Protein Diet: Comparison to Anti-EGFR Therapy. Cancers (Basel). 2021;13: pubmed publisher
Xu W, Cui J, Wu L, He C, Chen G. The role of PD-1/PD-L1 checkpoint in arsenic lung tumorigenesis. Toxicol Appl Pharmacol. 2021;426:115633 pubmed publisher
Gao L, Xia L, Ji W, Zhang Y, Xia W, Lu S. Knockdown of CDK5 down-regulates PD-L1 via the ubiquitination-proteasome pathway and improves antitumor immunity in lung adenocarcinoma. Transl Oncol. 2021;14:101148 pubmed publisher
Ling X, Han W, Jiang X, Chen X, Rodriguez M, Zhu P, et al. Point-source burst of coordination polymer nanoparticles for tri-modality cancer therapy. Biomaterials. 2021;270:120690 pubmed publisher
Yang P, Jiang Y, Rhea P, Coway T, Chen D, Gagea M, et al. Human Biofield Therapy and the Growth of Mouse Lung Carcinoma. Integr Cancer Ther. 2019;18:1534735419840797 pubmed publisher
Deng W, Zhu S, Zeng L, Liu J, Kang R, Yang M, et al. The Circadian Clock Controls Immune Checkpoint Pathway in Sepsis. Cell Rep. 2018;24:366-378 pubmed publisher
Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira N, et al. Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance. Nature. 2018;553:91-95 pubmed publisher

product information

master code :

MAB90781

SKU :

MAB90781-100

product name :

Mouse PD-L1/B7-H1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse PD-L1/B7-H1 Antibody from R&D Systems is a rabbit monoclonal antibody to PD-L1. This antibody reacts with human,mouse,xenograft. The Mouse PD-L1/B7-H1 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Neutralization,Immunohistochemistry,Flow Cytometry.

target :

PD-L1/B7-H1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

2096C

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse PD-L1/B7-H1, Met1-His239, Accession # Q9EP73

isotype :

IgG

purity :

Protein A or G purified from cell culture supernatant

species :

Human,Mouse

specificity :

Detects mouse PD-L1/B7-H1 in direct ELISAs and Western blots.

top caption :

Detection of Mouse PD-L1/B7-H1 antibody by Western Blot.

accessionNumbers :

Q9EP73

applications :

Immunocytochemistry,Western Blot,Neutralization,Immunohistochemistry,Flow Cytometry

extended description :

Recombinant Monoclonal Antibody.

USD :

489 USD

product details :

Recombinant Monoclonal Antibody.

alt names :

Avelumab, B7-H, B7H1, B7-H1, B7H1PDCD1L1, CD274, CD274 antigenMGC142294, CD274 molecule, PDCD1L1, PDCD1LG1, PDCD1LG1MGC142296, PDL1, PD-L1, PD-L1B7 homolog 1, PDL1PDCD1 ligand 1, programmed cell death 1 ligand 1, Programmed death ligand 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage