Human MMP-7 Antibody | R&D Systems MAB9071-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human MMP-7 Antibody

catalog :

MAB9071-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

111433

reactivity :

human

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 18

Reference
Lindgren M, Rask G, Jonsson J, Berglund A, Lundin C, Jonsson P, et al. Type IV Collagen in Human Colorectal Liver Metastases-Cellular Origin and a Circulating Biomarker. Cancers (Basel). 2022;14: pubmed publisher
Golizeh M, Winter K, Roussel L, Landekic M, Langelier M, Loo V, et al. Fecal host biomarkers predicting severity of Clostridioides difficile infection. JCI Insight. 2021;6: pubmed publisher
Chen Z, Zhu Y, Fan X, Liu Y, Feng Q. Upregulation of long non‑coding RNA CCEPR is associated with poor prognosis and contributes to the progression of ovarian cancer through regulating the Wnt/β‑catenin signaling pathway. Mol Med Rep. 2020;21:1950-1958 pubmed publisher
Bibby B, Miranda C, Reynolds J, Cawthorne C, Maher S. Silencing microRNA-330-5p increases MMP1 expression and promotes an invasive phenotype in oesophageal adenocarcinoma. BMC Cancer. 2019;19:784 pubmed publisher
Caporali S, Amaro A, Levati L, Alvino E, Lacal P, Mastroeni S, et al. miR-126-3p down-regulation contributes to dabrafenib acquired resistance in melanoma by up-regulating ADAM9 and VEGF-A. J Exp Clin Cancer Res. 2019;38:272 pubmed publisher
Alonso V, Escudero P, Fernandez Martos C, Salud A, Mendez M, Gallego J, et al. Coexpression of p-IGF-1R and MMP-7 Modulates Panitumumab and Cetuximab Efficacy in RAS Wild-Type Metastatic Colorectal Cancer Patients. Neoplasia. 2018;20:678-686 pubmed publisher
Bolenz C, Knauf D, John A, Erben P, Steidler A, Schneider S, et al. Decreased Invasion of Urothelial Carcinoma of the Bladder by Inhibition of Matrix-Metalloproteinase 7. Bladder Cancer. 2018;4:67-75 pubmed publisher
Guenzle J, Wolf L, Garrelfs N, Goeldner J, Osterberg N, Schindler C, et al. ATF3 reduces migration capacity by regulation of matrix metalloproteinases via NFκB and STAT3 inhibition in glioblastoma. Cell Death Discov. 2017;3:17006 pubmed publisher
Felli N, Errico M, Pedini F, Petrini M, Puglisi R, Bellenghi M, et al. AP2Î± controls the dynamic balance between miR-126&126* and miR-221&222 during melanoma progression. Oncogene. 2016;35:3016-26 pubmed publisher
Mierke C, Frey B, Fellner M, Herrmann M, Fabry B. Integrin ?5?1 facilitates cancer cell invasion through enhanced contractile forces. J Cell Sci. 2011;124:369-83 pubmed publisher
Szarvas T, Singer B, Becker M, vom Dorp F, Jager T, Szendroi A, et al. Urinary matrix metalloproteinase-7 level is associated with the presence of metastasis in bladder cancer. BJU Int. 2011;107:1069-73 pubmed publisher
Holland M, Jeffries D, Pattison M, Korr G, Gall A, Joof H, et al. Pathway-focused arrays reveal increased matrix metalloproteinase-7 (matrilysin) transcription in trachomatous trichiasis. Invest Ophthalmol Vis Sci. 2010;51:3893-902 pubmed publisher
Szarvas T, Becker M, vom Dorp F, Gethmann C, Totsch M, Bankfalvi A, et al. Matrix metalloproteinase-7 as a marker of metastasis and predictor of poor survival in bladder cancer. Cancer Sci. 2010;101:1300-8 pubmed publisher
Gogly B, Fournier B, Couty L, Naveau A, Brasselet C, Durand E, et al. Gingival fibroblast inhibits MMP-7: evaluation in an ex vivo aorta model. J Mol Cell Cardiol. 2009;47:296-303 pubmed publisher
Goswami S, Angkasekwinai P, Shan M, Greenlee K, Barranco W, Polikepahad S, et al. Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. Nat Immunol. 2009;10:496-503 pubmed publisher
Yu K, Barry C, Austin D, Busch C, Sangar V, Rustgi A, et al. Stable isotope dilution multidimensional liquid chromatography-tandem mass spectrometry for pancreatic cancer serum biomarker discovery. J Proteome Res. 2009;8:1565-76 pubmed publisher
Kong M, Gaggar A, Li Y, Winkler M, Blalock J, Clancy J. Matrix metalloproteinase activity in pediatric acute lung injury. Int J Med Sci. 2009;6:9-17 pubmed
Caruso R, Fina D, Peluso I, Fantini M, Tosti C, Del Vecchio Blanco G, et al. IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis. J Immunol. 2007;178:5957-65 pubmed

product information

brand :

R&D Systems

master code :

MAB9071

SKU :

MAB9071-100

product name :

Human MMP-7 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human MMP-7 Antibody from R&D Systems is a mouse monoclonal antibody to MMP-7. This antibody reacts with human,rabbit. The Human MMP-7 Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western.

target :

MMP-7

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

111433

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Simple Western 20 ug/mL, Immunohistochemistry 8-25 ug/mL, Immunoprecipitation 25 ug/mL

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human MMP-7, Leu18-Lys267 (Ala230del), Accession # NP_002414.1

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human,Rabbit

specificity :

Detects the pro and active forms of human MMP-7 in Western blots. In dot blots, approximately 20% cross-reactivity with recombinant human MMP-8 is observed and no cross-reactivity with recombinant human MMP-1, -2, -3, -9, -10, -12, or -13 is observed.

gene symbol :

MMP7

top caption :

Detection of Human MMP-7 antibody by Western Blot.

accessionNumbers :

NP_002414.1

applications :

Simple Western,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen

USD :

469 USD

alt names :

EC 3.4.24, EC 3.4.24.23, matrilysin, Matrin, matrix metallopeptidase 7 (matrilysin, uterine), matrix metalloproteinase 7 (matrilysin, uterine), Matrix metalloproteinase-7, MMP7, MMP-7, MPSL1, PUMP1, PUMP-1, Pump-1 protease, uterine matrilysin, Uterine metalloproteinase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage