Human MMP-1 Antibody | R&D Systems MAB901 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human MMP-1 Antibody

catalog :

MAB901

quantity :

200 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

36665

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section, dot blot

more info or order :

R&D Systems product webpage

citations: 39

Reference
Varga A, Németh I, Kemeny L, Varga J, Tiszlavicz L, Kumar D, et al. Elevated Serum Gastrin Is Associated with Melanoma Progression: Putative Role in Increased Migration and Invasion of Melanoma Cells. Int J Mol Sci. 2023;24: pubmed publisher
Gerwinn T, Salemi S, Schori L, Planta D, Eberli D, Horst M. Improved contractile potential in detrusor microtissues from pediatric patients with end stage lower urinary tract dysfunction. Front Cell Dev Biol. 2022;10:1007265 pubmed publisher
MacDonald W, Swaminathan S, Heo J, Castillejos A, Hsueh J, Liu B, et al. Effect of SPARC Suppression in Mice, Perfused Human Anterior Segments, and Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2022;63:8 pubmed publisher
Meunier M, Scandolera A, Chapuis E, Lapierre L, Sandr xe9 J, Brunner G, et al. The anti-wrinkles properties of sodium acetylated hyaluronate. J Cosmet Dermatol. 2022;21:2749-2762 pubmed publisher
Park J, Park H, Lee Y, Weon S, Kim Y, Yang J, et al. Blocking TNFα attenuates progressive cartilage matrix degradation in inflammatory arthritis. Exp Ther Med. 2021;22:808 pubmed publisher
Bhattacharya A, Janal M, Veeramachaneni R, Dolgalev I, Dubeykovskaya Z, Tu N, et al. Oncogenes overexpressed in metastatic oral cancers from patients with pain: potential pain mediators released in exosomes. Sci Rep. 2020;10:14724 pubmed publisher
Roztocil E, Hammond C, Gonzalez M, Feldon S, Woeller C. The aryl hydrocarbon receptor pathway controls matrix metalloproteinase-1 and collagen levels in human orbital fibroblasts. Sci Rep. 2020;10:8477 pubmed publisher
Du R, Lei T. Effects of autologous platelet-rich plasma injections on facial skin rejuvenation. Exp Ther Med. 2020;19:3024-3030 pubmed publisher
Yang P, Liu Y, Chang Y, Lin C, Huang P, Hua K, et al. Cabozantinib (XL184) and R428 (BGB324) Inhibit the Growth of Esophageal Squamous Cell Carcinoma (ESCC). Front Oncol. 2019;9:1138 pubmed publisher
Obama T, Ohinata H, Takaki T, Iwamoto S, Sawada N, Aiuchi T, et al. Cooperative Action of Oxidized Low-Density Lipoproteins and Neutrophils on Endothelial Inflammatory Responses Through Neutrophil Extracellular Trap Formation. Front Immunol. 2019;10:1899 pubmed publisher
Bibby B, Miranda C, Reynolds J, Cawthorne C, Maher S. Silencing microRNA-330-5p increases MMP1 expression and promotes an invasive phenotype in oesophageal adenocarcinoma. BMC Cancer. 2019;19:784 pubmed publisher
Młynarczyk G, Kudelski J, Darewicz B, Bruczko Goralewska M, Romanowicz L. Suppressed Expression but Not Activity of Collagenases MMP-1 and MMP-13 in Human Renal Carcinoma. Pathobiology. 2019;:1-7 pubmed publisher
Kim M, Son D, Shin S, Park D, Byun S, Jung E. Protective effects of Camellia japonica flower extract against urban air pollutants. BMC Complement Altern Med. 2019;19:30 pubmed publisher
de Pizzol Júnior J, Sasso Cerri E, Cerri P. Matrix Metalloproteinase-1 and Acid Phosphatase in the Degradation of the Lamina Propria of Eruptive Pathway of Rat Molars. Cells. 2018;7: pubmed publisher
Han A, Lim T, Song Y, Jang M, Rhee Y, Hong H, et al. Inhibitory Effect of Opuntia humifusa Fruit Water Extract on Solar Ultraviolet-Induced MMP-1 Expression. Int J Mol Sci. 2018;19: pubmed publisher
Macarie R, Vadana M, Ciortan L, Tucureanu M, Ciobanu A, Vinereanu D, et al. The expression of MMP-1 and MMP-9 is up-regulated by smooth muscle cells after their cross-talk with macrophages in high glucose conditions. J Cell Mol Med. 2018;22:4366-4376 pubmed publisher
Huang X, Zhong L, Post J, Karperien M. Co-treatment of TGF-?3 and BMP7 is superior in stimulating chondrocyte redifferentiation in both hypoxia and normoxia compared to single treatments. Sci Rep. 2018;8:10251 pubmed publisher
Huang X, Zhong L, Hendriks J, Post J, Karperien M. The Effects of the WNT-Signaling Modulators BIO and PKF118-310 on the Chondrogenic Differentiation of Human Mesenchymal Stem Cells. Int J Mol Sci. 2018;19: pubmed publisher
Brilha S, Ong C, Weksler B, Romero N, Couraud P, Friedland J. Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis. Sci Rep. 2017;7:16031 pubmed publisher
Rattanasinchai C, Llewellyn B, Conrad S, Gallo K. MLK3 regulates FRA-1 and MMPs to drive invasion and transendothelial migration in triple-negative breast cancer cells. Oncogenesis. 2017;6:e345 pubmed publisher
Yan S, Yang B, Shang C, Ma Z, Tang Z, Liu G, et al. Platelet‑rich plasma promotes the migration and invasion of synovial fibroblasts in patients with rheumatoid arthritis. Mol Med Rep. 2016;14:2269-75 pubmed publisher
Farooqui M, Bohrer L, Brady N, Chuntova P, Kemp S, Wardwell C, et al. Epiregulin contributes to breast tumorigenesis through regulating matrix metalloproteinase 1 and promoting cell survival. Mol Cancer. 2015;14:138 pubmed publisher
Ã…gren M, Schnabel R, Christensen L, Mirastschijski U. Tumor necrosis factor-Î±-accelerated degradation of type I collagen in human skin is associated with elevated matrix metalloproteinase (MMP)-1 and MMP-3 ex vivo. Eur J Cell Biol. 2015;94:12-21 pubmed publisher
Du X, Lin B, Wang Q, Li H, Ingalla E, Tien J, et al. MMP-1 and Pro-MMP-10 as potential urinary pharmacodynamic biomarkers of FGFR3-targeted therapy in patients with bladder cancer. Clin Cancer Res. 2014;20:6324-35 pubmed publisher
Bartling T, Subbaram S, Clark R, Chandrasekaran A, Kar S, Melendez J. Redox-sensitive gene-regulatory events controlling aberrant matrix metalloproteinase-1 expression. Free Radic Biol Med. 2014;74:99-107 pubmed publisher
CAMPBELL L, Lee A, Rosenfeld M, Kuo C. Chlamydia pneumoniae induces expression of pro-atherogenic factors through activation of the lectin-like oxidized LDL receptor-1. Pathog Dis. 2013;69:1-6 pubmed
Holmberg C, Ghesquière B, Impens F, Gevaert K, Kumar J, Cash N, et al. Mapping proteolytic processing in the secretome of gastric cancer-associated myofibroblasts reveals activation of MMP-1, MMP-2, and MMP-3. J Proteome Res. 2013;12:3413-22 pubmed publisher
Hasegawa A, Nakahara H, Kinoshita M, Asahara H, Koziol J, Lotz M. Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis. Arthritis Res Ther. 2013;15:R29 pubmed publisher
Li R, Ackerman W, Mihai C, Volakis L, GHADIALI S, Kniss D. Myoferlin depletion in breast cancer cells promotes mesenchymal to epithelial shape change and stalls invasion. PLoS ONE. 2012;7:e39766 pubmed publisher
Dasgupta J, Kar S, Liu R, Joseph J, Kalyanaraman B, Remington S, et al. Reactive oxygen species control senescence-associated matrix metalloproteinase-1 through c-Jun-N-terminal kinase. J Cell Physiol. 2010;225:52-62 pubmed publisher
Cavallo C, Desando G, Facchini A, Grigolo B. Chondrocytes from patients with osteoarthritis express typical extracellular matrix molecules once grown onto a three-dimensional hyaluronan-based scaffold. J Biomed Mater Res A. 2010;93:86-95 pubmed publisher
Ooi Y, Oh D, Rhee D. Effect of bimatoprost, latanoprost, and unoprostone on matrix metalloproteinases and their inhibitors in human ciliary body smooth muscle cells. Invest Ophthalmol Vis Sci. 2009;50:5259-65 pubmed publisher
Villeneuve J, Block A, Le Bousse Kerdiles M, Lepreux S, Nurden P, Ripoche J, et al. Tissue inhibitors of matrix metalloproteinases in platelets and megakaryocytes: a novel organization for these secreted proteins. Exp Hematol. 2009;37:849-56 pubmed publisher
Kong M, Gaggar A, Li Y, Winkler M, Blalock J, Clancy J. Matrix metalloproteinase activity in pediatric acute lung injury. Int J Med Sci. 2009;6:9-17 pubmed
Naveau A, Reinald N, Fournier B, Durand E, Lafont A, Coulomb B, et al. Gingival fibroblasts inhibit MMP-1 and MMP-3 activities in an ex-vivo artery model. Connect Tissue Res. 2007;48:300-8 pubmed
Lazer G, Pe er L, Schapira V, Richard S, Katzav S. The association of Sam68 with Vav1 contributes to tumorigenesis. Cell Signal. 2007;19:2479-86 pubmed
Lauder S, Carty S, Carpenter C, Hill R, Talamas F, Bondeson J, et al. Interleukin-1beta induced activation of nuclear factor-kappab can be inhibited by novel pharmacological agents in osteoarthritis. Rheumatology (Oxford). 2007;46:752-8 pubmed
Monteleone G, Caruso R, Fina D, Peluso I, Gioia V, Stolfi C, et al. Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21. Gut. 2006;55:1774-80 pubmed
Edwards S, Cruz A, Donnelly S, Dazin P, Schulman E, Jones K, et al. c-Kit immunophenotyping and metalloproteinase expression profiles of mast cells in interstitial lung diseases. J Pathol. 2005;206:279-90 pubmed

product information

brand :

R&D Systems

master code :

MAB901

SKU :

MAB901

product name :

Human MMP-1 Antibody

unit size :

200 ug (also 25 ug)

seo description :

The Human MMP-1 Antibody from R&D Systems is a mouse monoclonal antibody to MMP-1. This antibody reacts with human. The Human MMP-1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,ELISA Development,Dot Blot,Neutralization,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunoprecipitation,Knockout Validated.

target :

MMP-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

36665

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 2 ug/mL, Immunohistochemistry 8-25 ug/mL, Immunoprecipitation 25 ug/mL, Neutralization 200 ug/mL, Knockout Validated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human MMP-1, Phe20-Asn469, Accession # P03956

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects pro and active forms of human MMP-1. In Western blots, no cross-reactivity with recombinant human (rh) MMP-2, rhMMP-3, or rhMMP-9 is observed.

gene symbol :

MMP1

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human MMP-1 antibody by Western Blot.

accessionNumbers :

P03956

applications :

Immunoprecipitation,Knockout Validated,ELISA Development,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Dot Blot,Neutralization,Immunocytochemistry

USD :

489 USD

alt names :

CLGmatrix metalloprotease 1, CLGN, EC 3.4.24, EC 3.4.24.7, Fibroblast collagenase, interstitial collagenase, matrix metallopeptidase 1 (interstitial collagenase), matrix metalloproteinase 1 (interstitial collagenase), Matrix metalloproteinase-1, MMP1, MMP-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage