Human Mer Antibody | R&D Systems MAB8912 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Mer Antibody

catalog :

MAB8912

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

125518

reactivity :

human

application :

flow cytometry

citations: 5

Reference
Bernsmeier C, Triantafyllou E, Brenig R, Lebosse F, Singanayagam A, Patel V, et al. CD14+ CD15- HLA-DR- myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure. Gut. 2018;67:1155-1167 pubmed publisher
Happonen K, Tran S, MÃ¶rgelin M, Prince R, Calzavarini S, Angelillo Scherrer A, et al. The Gas6-Axl Protein Interaction Mediates Endothelial Uptake of Platelet Microparticles. J Biol Chem. 2016;291:10586-601 pubmed publisher
Bauer T, Zagorska A, Jurkin J, Yasmin N, Köffel R, Richter S, et al. Identification of Axl as a downstream effector of TGF-?1 during Langerhans cell differentiation and epidermal homeostasis. J Exp Med. 2012;209:2033-47 pubmed publisher
Hurtado B, Munoz X, Recarte Pelz P, Garcia N, Luque A, Krupinski J, et al. Expression of the vitamin K-dependent proteins GAS6 and protein S and the TAM receptor tyrosine kinases in human atherosclerotic carotid plaques. Thromb Haemost. 2011;105:873-82 pubmed publisher
Shiozawa Y, Pedersen E, Taichman R. GAS6/Mer axis regulates the homing and survival of the E2A/PBX1-positive B-cell precursor acute lymphoblastic leukemia in the bone marrow niche. Exp Hematol. 2010;38:132-40 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB8912

SKU :

MAB8912-100

product name :

Human Mer Antibody

description :

The Human Mer Antibody from R&D Systems is a mouse monoclonal antibody to Mer. This antibody reacts with human. The Human Mer Antibody has been validated for the following applications: Flow Cytometry, CyTOF-ready, Knockout Validated, ELISA Capture (Matched Antibody Pair).

target :

Mer

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

125518

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Mer, Met1-Ala499, Accession # AAB60430

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Mer in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) Axl, rhDtk, or recombinant mouse Mer is observed.

gene symbol :

MERTK

details of functionality :

ActivityAssaywCitation not found None None None

catalog number base :

MAB8912

accessionNumbers :

AAB60430

applications :

Flow Cytometry, CyTOF-ready, Knockout Validated, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

369 USD

alt names :

c-Eyk, C-mer, c-mer proto-oncogene tyrosine kinase, EC 2.7.10, EC 2.7.10.1, MER, MER receptor tyrosine kinase, MerTK, MGC133349, Receptor tyrosine kinase MerTK, RP38Proto-oncogene c-Mer, STK kinase, tyrosine-protein kinase Mer

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.