product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Mer Antibody
catalog :
MAB8911
quantity :
500 ug (also 25 ug)
price :
599 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
125508
reactivity :
human
application :
western blot, neutralization, immunohistochemistry - frozen section
more info or order :
citations: 3
Reference
Garbin U, Baggio E, Stranieri C, Pasini A, Manfro S, Mozzini C, et al. Expansion of necrotic core and shedding of Mertk receptor in human carotid plaques: a role for oxidized polyunsaturated fatty acids?. Cardiovasc Res. 2013;97:125-33 pubmed publisher
Zahuczky G, Kristóf E, Majai G, Fesus L. Differentiation and glucocorticoid regulated apopto-phagocytic gene expression patterns in human macrophages. Role of Mertk in enhanced phagocytosis. PLoS ONE. 2011;6:e21349 pubmed publisher
Weinger J, Omari K, Marsden K, Raine C, Shafit Zagardo B. Up-regulation of soluble Axl and Mer receptor tyrosine kinases negatively correlates with Gas6 in established multiple sclerosis lesions. Am J Pathol. 2009;175:283-93 pubmed publisher
product information
master code :
MAB8911
SKU :
MAB8911
product name :
Human Mer Antibody
unit size :
500 ug (also 25 ug)
description :
The Human Mer Antibody from R&D Systems is a mouse monoclonal antibody to Mer. This antibody reacts with human. The Human Mer Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry-Frozen.
target :
Mer
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
125508
conjugate :
Unconjugated
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Mer, Ala21-Ala499, Accession # Q12866.2
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Mer in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant human (rh) Axl, rhDtk, or rmMer.
gene symbol :
MERTK
accessionNumbers :
Q12866.2
applications :
Western Blot,Neutralization,Immunohistochemistry-Frozen
USD :
599 USD
alt names :
c-Eyk, C-mer, c-mer proto-oncogene tyrosine kinase, EC 2.7.10, EC 2.7.10.1, MER, MER receptor tyrosine kinase, MerTK, MGC133349, Receptor tyrosine kinase MerTK, RP38Proto-oncogene c-Mer, STK kinase, tyrosine-protein kinase Mer
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.