Human IL-10 R beta Antibody | R&D Systems MAB874 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-10 R beta Antibody

catalog :

MAB874

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

90220

reactivity :

human

application :

western blot, neutralization, flow cytometry

citations: 5

Reference
Obajemu A, Rao N, Dilley K, Vargas J, Sheikh F, Donnelly R, et al. IFN-Î»4 Attenuates Antiviral Responses by Enhancing Negative Regulation of IFN Signaling. J Immunol. 2017;199:3808-3820 pubmed publisher
Kelly A, Robinson M, Roche G, Biron C, O Farrelly C, Ryan E. Immune Cell Profiling of IFN-? Response Shows pDCs Express Highest Level of IFN-?R1 and Are Directly Responsive via the JAK-STAT Pathway. J Interferon Cytokine Res. 2016;36:671-680 pubmed
Akil H, Abbaci A, LallouÃ© F, Bessette B, Costes L, Domballe L, et al. IL22/IL-22R pathway induces cell survival in human glioblastoma cells. PLoS ONE. 2015;10:e0119872 pubmed publisher
Gruber S, Gloria Luciani M, Grundtner P, Zdanov A, Gasche C. Differential signaling of cmvIL-10 through common variants of the IL-10 receptor 1. Eur J Immunol. 2008;38:3365-75 pubmed publisher
Jenkins C, Garcia W, Godwin M, Spencer J, Stern J, Abendroth A, et al. Immunomodulatory properties of a viral homolog of human interleukin-10 expressed by human cytomegalovirus during the latent phase of infection. J Virol. 2008;82:3736-50 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB874

SKU :

MAB874-100

product name :

Human IL-10 R beta Antibody

description :

The Human IL-10 R beta Antibody from R&D Systems is a mouse monoclonal antibody to IL-10 R beta. This antibody reacts with human. The Human IL-10 R beta Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Neutralization, CyTOF-ready.

target :

IL-10 R beta

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

90220

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human IL-10 R beta , Met20-Ser220, Accession # Q08334

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human IL-10 R beta in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-10 R alpha , rhIFN-gamma RI, and rhIFN-gamma R2 is observed.

gene symbol :

IL10RB

details of functionality :

ActivityAssaywCitation not found None None None

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB874

accessionNumbers :

Q08334

applications :

Western Blot, Flow Cytometry, Neutralization, CyTOF-ready

2020 USD :

339

2021 USD :

359 USD

alt names :

CDw210b, CDw210b antigen, CRF2-4IL-10R subunit 2, CRFB4, CRFB4human transmembrane receptor protein; cytokine receptor10CDW210B, D21S58, D21S66, IBD25, IL-10 receptor subunit beta, IL10R beta, IL-10R2, IL-10R2IL-10R subunit beta, IL10RB, IL-10RB, interleukin 10 receptor, beta, Interleukin-10 receptor subunit 2, interleukin-10 receptor subunit beta, member 4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.