product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Phospho-p38 alpha (T180/Y182) Antibody
catalog :
MAB8691
quantity :
100 ug (also 25 ug)
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
696602
reactivity :
human, mouse
application :
western blot
more info or order :
citations: 10
Reference
x15a witalska M, Filip Psurska B, Milczarek M, Psurski M, Moszy x144 ska A, D x105 browska A, et al. Combined anticancer therapy with imidazoacridinone analogue C-1305 and paclitaxel in human lung and colon cancer xenografts-Modulation of tumour angiogenesis. J Cell Mol Med. 2022;26:3950-3964 pubmed publisher
Lepore Signorile M, Grossi V, Di Franco S, Forte G, Disciglio V, Fasano C, et al. Pharmacological targeting of the novel β-catenin chromatin-associated kinase p38α in colorectal cancer stem cell tumorspheres and organoids. Cell Death Dis. 2021;12:316 pubmed publisher
Kanmani P, Ansari A, Villena J, Kim H. Immunobiotics Beneficially Modulate TLR4 Signaling Triggered by Lipopolysaccharide and Reduce Hepatic Steatosis In Vitro. J Immunol Res. 2019;2019:3876896 pubmed publisher
Simões Sousa S, Littler S, Thompson S, Minshall P, Whalley H, Bakker B, et al. The p38α Stress Kinase Suppresses Aneuploidy Tolerance by Inhibiting Hif-1α. Cell Rep. 2018;25:749-760.e6 pubmed publisher
Kanmani P, Kim H. Protective Effects of Lactic Acid Bacteria Against TLR4 Induced Inflammatory Response in Hepatoma HepG2 Cells Through Modulation of Toll-Like Receptor Negative Regulators of Mitogen-Activated Protein Kinase and NF-κB Signaling. Front Immunol. 2018;9:1537 pubmed publisher
Lei X, Cai L, Li X, Xu H, Geng C, Wang C. Up-regulation of NHE8 by somatostatin ameliorates the diarrhea symptom in infectious colitis mice model. Korean J Physiol Pharmacol. 2018;22:269-275 pubmed publisher
Park K, Kim J, Lee E, Lee T. Cynandione A inhibits lipopolysaccharide-induced cell adhesion via suppression of the protein expression of VCAM‑1 in human endothelial cells. Int J Mol Med. 2018;41:1756-1764 pubmed publisher
Tateosian N, Pellegrini J, Amiano N, Rolandelli A, Casco N, Palmero D, et al. IL17A augments autophagy in Mycobacterium tuberculosis-infected monocytes from patients with active tuberculosis in association with the severity of the disease. Autophagy. 2017;13:1191-1204 pubmed publisher
Bublik D, Bursać S, Sheffer M, Orsolic I, Shalit T, Tarcic O, et al. Regulatory module involving FGF13, miR-504, and p53 regulates ribosomal biogenesis and supports cancer cell survival. Proc Natl Acad Sci U S A. 2017;114:E496-E505 pubmed publisher
Huang C, Li H, Wu N, Hsiao C, Lin C, Chang H, et al. Photoprotective Effects of Cycloheterophyllin against UVA-Induced Damage and Oxidative Stress in Human Dermal Fibroblasts. PLoS ONE. 2016;11:e0161767 pubmed publisher
product information
master code :
MAB8691
SKU :
MAB8691
product name :
Human Phospho-p38 alpha (T180/Y182) Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Phospho-p38 alpha (T180/Y182) Antibody from R&D Systems is a mouse monoclonal antibody to p38 alpha. This antibody reacts with human,mouse,xenograft. The Human Phospho-p38 alpha (T180/Y182) Antibody has been validated for the following applications: Western Blot,Simple Western.
target :
p38 alpha
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
696602
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Phosphopeptide containing the human p38 alpha T180/Y182 site, Accession # Q16539
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Xenograft
specificity :
Detects human p38 alpha when phosphorylated at T180 and Y182.
gene symbol :
MAPK14
top caption :
Detection of Human Phospho-p38a (T180/Y182) antibody by Western Blot.
accessionNumbers :
Q16539
applications :
Western Blot,Simple Western
USD :
439 USD
alt names :
CSBP;CSBP1;CSBP2;CSPB1;EXIP;MAPK14;Mitogen-activated protein kinase;Mitogen-activated protein kinase 14;Mxi2;p38;p38ALPHA;PRKM14;PRKM15;RK;SAPK2A, MAPK14, SAPK2a
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.