Human APAF-1 Antibody | R&D Systems MAB868 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human APAF-1 Antibody

catalog :

MAB868

quantity :

100 ug (also 25 ug)

price :

349 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

94408

reactivity :

human, rat, chicken

application :

western blot, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Rodrigues Moita A, Bandolik J, Hansen F, Kurz T, Hamacher A, Kassack M. Priming with HDAC Inhibitors Sensitizes Ovarian Cancer Cells to Treatment with Cisplatin and HSP90 Inhibitors. Int J Mol Sci. 2020;21: pubmed publisher
Hayes H, Peterson B, Haldeman J, Newgard C, Hohmeier H, Stephens S. Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival. PLoS ONE. 2017;12:e0172567 pubmed publisher
Mungamuri S, Wang S, Manfredi J, Gu W, Aaronson S. Ash2L enables P53-dependent apoptosis by favoring stable transcription pre-initiation complex formation on its pro-apoptotic target promoters. Oncogene. 2015;34:2461-70 pubmed publisher
Kracikova M, Akiri G, George A, Sachidanandam R, Aaronson S. A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis. Cell Death Differ. 2013;20:576-88 pubmed publisher
Bano D, Dinsdale D, Cabrera Socorro A, Maida S, Lambacher N, McColl B, et al. Alteration of the nuclear pore complex in Ca(2+)-mediated cell death. Cell Death Differ. 2010;17:119-33 pubmed publisher
Karki P, Seong C, Kim J, Hur K, Shin S, Lee J, et al. Intracellular K(+) inhibits apoptosis by suppressing the Apaf-1 apoptosome formation and subsequent downstream pathways but not cytochrome c release. Cell Death Differ. 2007;14:2068-75 pubmed
Sato T, Machida T, Takahashi S, Iyama S, Sato Y, Kuribayashi K, et al. Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells. J Immunol. 2004;173:285-96 pubmed
Sanders E, Parker E. The role of mitochondria, cytochrome c and caspase-9 in embryonic lens fibre cell denucleation. J Anat. 2002;201:121-35 pubmed

product information

master code :

MAB868

SKU :

MAB868

product name :

Human APAF-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human APAF-1 Antibody from R&D Systems is a mouse monoclonal antibody to APAF-1. This antibody reacts with avian - chicken,human,rat. The Human APAF-1 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry.

target :

APAF-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

94408

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human APAF-1, Leu10-Asp214, Accession # AAC51678

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Avian - Chicken,Human,Rat

specificity :

Detects human APAF-1 in Western blots.

gene symbol :

APAF1

top caption :

Detection of Human APAF-1 antibody by Western Blot.

accessionNumbers :

AAC51678

applications :

Western Blot,Immunocytochemistry

USD :

349 USD

alt names :

APAF1, APAF-1apoptotic protease activating factor 1, apoptotic peptidase activating factor, apoptotic peptidase activating factor 1, apoptotic protease activating factor, apoptotic protease-activating factor 1, CED4, DKFZp781B1145, KIAA0413

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage