Human Tyro3/Dtk Antibody | R&D Systems MAB859 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Tyro3/Dtk Antibody

catalog :

MAB859

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

96201

reactivity :

human

application :

immunohistochemistry, flow cytometry

citations: 7

Reference
Cross S, Potter J, Aldo P, Kwon J, Pitruzzello M, Tong M, et al. Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation. J Immunol. 2017;199:2885-2895 pubmed publisher
Aagaard K, Lahon A, Suter M, Arya R, Seferovic M, Vogt M, et al. Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication. Sci Rep. 2017;7:41389 pubmed publisher
Bauer T, Zagorska A, Jurkin J, Yasmin N, Köffel R, Richter S, et al. Identification of Axl as a downstream effector of TGF-?1 during Langerhans cell differentiation and epidermal homeostasis. J Exp Med. 2012;209:2033-47 pubmed publisher
Shimojima M, Stroher U, Ebihara H, Feldmann H, Kawaoka Y. Identification of cell surface molecules involved in dystroglycan-independent Lassa virus cell entry. J Virol. 2012;86:2067-78 pubmed publisher
Clauser S, Meilhac O, Bieche I, Raynal P, Bruneval P, Michel J, et al. Increased secretion of Gas6 by smooth muscle cells in human atherosclerotic carotid plaques. Thromb Haemost. 2012;107:140-9 pubmed publisher
Zhu D, Wang Y, Singh I, Bell R, Deane R, Zhong Z, et al. Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor. Blood. 2010;115:4963-72 pubmed publisher
Weinger J, Omari K, Marsden K, Raine C, Shafit Zagardo B. Up-regulation of soluble Axl and Mer receptor tyrosine kinases negatively correlates with Gas6 in established multiple sclerosis lesions. Am J Pathol. 2009;175:283-93 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB859

SKU :

MAB859-100

product name :

Human Tyro3/Dtk Antibody

description :

The Human Tyro3/Dtk Antibody from R&D Systems is a mouse monoclonal antibody to Dtk/TYRO3. This antibody reacts with human. The Human Tyro3/Dtk Antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Knockout Validated, ELISA Capture (Matched Antibody Pair).

target :

Dtk/TYRO3

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

96201

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Tyro3/Dtk, Ala41-Ser428 (predicted), Accession # Q06418

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Tyro3/Dtk in ELISAs and Western blots. In ELISAs and Western blots, no cross-reactivity or interferance with recombinant mouse Tyro3/Dtk, recombinant human (rh) Axl, or rhMer is observed.

gene symbol :

TYRO3

catalog number base :

MAB859

accessionNumbers :

Q06418

applications :

Flow Cytometry, Immunohistochemistry, Knockout Validated, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

359 USD

alt names :

Brt, BYK, Dtk, EC 2.7.10, EC 2.7.10.1, FLJ16467, RSE, Sky, Tif, TYRO3 protein tyrosine kinase, Tyrosine-protein kinase byk, Tyrosine-protein kinase DTK, tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.