Tyro3/Dtk Antibody | R&D Systems MAB859-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Tyro3/Dtk Antibody

catalog :

MAB859-100

quantity :

100 ug (also 500 ug, 25 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

96201

reactivity :

human

application :

ELISA, immunohistochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Xue J, Xu L, Zhu H, Bai M, Li X, Zhao Z, et al. CD14+CD16- monocytes are the main precursors of osteoclasts in rheumatoid arthritis via expressing Tyro3TK. Arthritis Res Ther. 2020;22:221 pubmed publisher
Cross S, Potter J, Aldo P, Kwon J, Pitruzzello M, Tong M, et al. Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation. J Immunol. 2017;199:2885-2895 pubmed publisher
Aagaard K, Lahon A, Suter M, Arya R, Seferovic M, Vogt M, et al. Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication. Sci Rep. 2017;7:41389 pubmed publisher
Bauer T, Zagorska A, Jurkin J, Yasmin N, Köffel R, Richter S, et al. Identification of Axl as a downstream effector of TGF-?1 during Langerhans cell differentiation and epidermal homeostasis. J Exp Med. 2012;209:2033-47 pubmed publisher
Shimojima M, Stroher U, Ebihara H, Feldmann H, Kawaoka Y. Identification of cell surface molecules involved in dystroglycan-independent Lassa virus cell entry. J Virol. 2012;86:2067-78 pubmed publisher
Clauser S, Meilhac O, Bieche I, Raynal P, Bruneval P, Michel J, et al. Increased secretion of Gas6 by smooth muscle cells in human atherosclerotic carotid plaques. Thromb Haemost. 2012;107:140-9 pubmed publisher
Zhu D, Wang Y, Singh I, Bell R, Deane R, Zhong Z, et al. Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor. Blood. 2010;115:4963-72 pubmed publisher
Weinger J, Omari K, Marsden K, Raine C, Shafit Zagardo B. Up-regulation of soluble Axl and Mer receptor tyrosine kinases negatively correlates with Gas6 in established multiple sclerosis lesions. Am J Pathol. 2009;175:283-93 pubmed publisher

image

image 1 :

Detection of Dtk antibody in K562 Human Cell Line antibody by Flow Cytometry.

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB859

SKU :

MAB859-100

product name :

Tyro3/Dtk Antibody

Description :

The Human Tyro3/Dtk Antibody from R&D Systems is a mouse monoclonal antibody to Dtk/TYRO3. This antibody reacts with human. The Human Tyro3/Dtk Antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Knockout Validated, ELISA Capture (Matched Antibody Pair).

target :

Tyro3/Dtk

category :

Primary Antibodies

unit size :

100 ug (also 500 ug, 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

96201

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Tyro3/Dtk, Ala41-Ser428 (predicted), Accession # Q06418

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Tyro3/Dtk in ELISAs and Western blots. In ELISAs and Western blots, no cross-reactivity or interferance with recombinant mouse Tyro3/Dtk, recombinant human (rh) Axl, or rhMer is observed.

gene symbol :

TYRO3

accessionNumbers :

Q06418

applications :

Flow Cytometry, Immunohistochemistry, Knockout Validated, ELISA Capture (Matched Antibody Pair)

USD :

459 USD

alt names :

Brt, BYK, Dtk, EC 2.7.10, EC 2.7.10.1, FLJ16467, RSE, Sky, Tif, TYRO3 protein tyrosine kinase, Tyrosine-protein kinase byk, Tyrosine-protein kinase DTK, tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage