Human/Mouse PTEN Antibody | R&D Systems MAB847 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse PTEN Antibody

catalog :

MAB847

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

217702

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 6

Reference
Mohammad M, Greenman J, Maraveyas A, Ettelaie C. Activation of PAR2 by tissue factor induces the release of the PTEN from MAGI proteins and regulates PTEN and Akt activities. Sci Rep. 2020;10:20908 pubmed publisher
Post K, Belmadani M, Ganguly P, Meili F, Dingwall R, McDiarmid T, et al. Multi-model functionalization of disease-associated PTEN missense mutations identifies multiple molecular mechanisms underlying protein dysfunction. Nat Commun. 2020;11:2073 pubmed publisher
Delic Jukic I, Kostic S, Filipović N, Gudelj Ensor L, Ivandic M, Dukic J, et al. Changes in expression of special AT-rich sequence binding protein 1 and phosphatase and tensin homologue in kidneys of diabetic rats during ageing. Nephrol Dial Transplant. 2018;33:1734-1741 pubmed publisher
Petkau G, Kawano Y, Wolf I, Knoll M, Melchers F. MiR221 promotes precursor B-cell retention in the bone marrow by amplifying the PI3K-signaling pathway in mice. Eur J Immunol. 2018;48:975-989 pubmed publisher
Yang Z, Tang X, Guo X, Zou D, Sun X, Feng J, et al. Cancer cell-oriented migration of mesenchymal stem cells engineered with an anticancer gene (PTEN): an imaging demonstration. Onco Targets Ther. 2014;7:441-6 pubmed publisher
Wu H, Wang S, Weng D, Xing H, Song X, Zhu T, et al. Reversal of the malignant phenotype of ovarian cancer A2780 cells through transfection with wild-type PTEN gene. Cancer Lett. 2008;271:205-14 pubmed publisher

product information

master code :

MAB847

SKU :

MAB847

product name :

Human/Mouse PTEN Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse PTEN Antibody from R&D Systems is a mouse monoclonal antibody to PTEN. This antibody reacts with human,mouse,rat. The Human/Mouse PTEN Antibody has been validated for the following applications: ELISA Development,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunohistochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready,Knockout Validated.

target :

PTEN

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

217702

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human PTEN, Thr2-Val403, Accession # P60484

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects human and mouse PTEN.

gene symbol :

PTEN

accessionNumbers :

P60484

applications :

ELISA Development,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunohistochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready,Knockout Validated

USD :

479 USD

alt names :

BZS, EC 3.1.3.16,10q23del, EC 3.1.3.48, EC 3.1.3.67, GLM2, MMAC1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1MGC11227, Mutated in multiple advanced cancers 1, phosphatase and tensin homologDEC, phosphatidylinositol-34,5-trisphosphate 3-phosphatase and dual-specificityprotein phosphatase PTEN, PTEN1, TEP1MHAM

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage