Human IL-18 R alpha/IL-1 R5 Antibody | R&D Systems MAB840 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-18 R alpha/IL-1 R5 Antibody

catalog :

MAB840

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

70625

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

citations: 9

Reference
Lin L, Wang J, Liu D, Liu S, Xu H, Ji N, et al. Interleukin-37 expression and its potential role in oral leukoplakia and oral squamous cell carcinoma. Sci Rep. 2016;6:26757 pubmed publisher
Wang J, Sun C, Gerdes N, Liu C, Liao M, Liu J, et al. Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter. Nat Med. 2015;21:820-6 pubmed publisher
Li W, Okuda A, Yamamoto H, Yamanishi K, Terada N, Yamanishi H, et al. Regulation of development of CD56 bright CD11c + NK-like cells with helper function by IL-18. PLoS ONE. 2013;8:e82586 pubmed publisher
Blom L, Poulsen L. IL-1 family members IL-18 and IL-33 upregulate the inflammatory potential of differentiated human Th1 and Th2 cultures. J Immunol. 2012;189:4331-7 pubmed publisher
Takei S, Hoshino T, Matsunaga K, Sakazaki Y, Sawada M, Oda H, et al. Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis. Arthritis Res Ther. 2011;13:R52 pubmed publisher
Tucci M, Quatraro C, Lombardi L, Pellegrino C, Dammacco F, Silvestris F. Glomerular accumulation of plasmacytoid dendritic cells in active lupus nephritis: role of interleukin-18. Arthritis Rheum. 2008;58:251-62 pubmed publisher
Rao D, Tracey K, Pober J. IL-1alpha and IL-1beta are endogenous mediators linking cell injury to the adaptive alloimmune response. J Immunol. 2007;179:6536-46 pubmed
Zola H, Swart B, Banham A, Barry S, Beare A, Bensussan A, et al. CD molecules 2006--human cell differentiation molecules. J Immunol Methods. 2007;319:1-5 pubmed
Ebert E, Mehta V. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell Immunol. 2006;241:7-13 pubmed

product information

brand :

R&D Systems

master code :

MAB840

SKU :

MAB840-100

product name :

Human IL-18 R alpha/IL-1 R5 Antibody

description :

The Human IL-18 R alpha/IL-1 R5 Antibody from R&D Systems is a mouse monoclonal antibody to IL-18R alpha/IL-1 R5. This antibody reacts with human. The Human IL-18 R alpha/IL-1 R5 Antibody has been validated for the following applications: Flow Cytometry, Immunohistochemistry, Neutralization, Immunocytochemistry, CyTOF-ready.

target :

IL-18R alpha/IL-1 R5

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

70625

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human IL-18 R alpha/IL-1 R5, Glu20-Arg329, Accession # Q13478

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects Recombinant Human IL-18 R alpha/IL-1 R5 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-1 RI, rhIL-1 RII, rhIL-1 R3, rhIL-1 R4, rhIL-1 R6, rhIL-1 R7, rhIL-1 R8, rhIL-1 R9, rhSIGIRR or recombinant mouse IL-18 R alpha is observed.

gene symbol :

IL18R1

details of functionality :

ActivityAssaywCitation not found None None None None

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB840

accessionNumbers :

Q13478

applications :

Flow Cytometry, Immunohistochemistry, Neutralization, Immunocytochemistry, CyTOF-ready

2020 USD :

339

2021 USD :

359 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.