product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat HHEX Antibody
catalog :
MAB83771-100
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
2018B
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, flow cytometry, chromatin immunoprecipitation
more info or order :
citations: 6
Reference
Ito R, Kimura A, Hirose Y, Hatano Y, Mima A, Mae S, et al. Elucidation of HHEX in pancreatic endoderm differentiation using a human iPSC differentiation model. Sci Rep. 2023;13:8659 pubmed publisher
Wong Y, Kumar Y, Proks M, Herrera J, Rothov xe1 M, Monteiro R, et al. Expansion of ventral foregut is linked to changes in the enhancer landscape for organ-specific differentiation. Nat Cell Biol. 2023;25:481-492 pubmed publisher
Yang D, Cho H, Tayyebi Z, Shukla A, Luo R, Dixon G, et al. CRISPR screening uncovers a central requirement for HHEX in pancreatic lineage commitment and plasticity restriction. Nat Cell Biol. 2022;24:1064-1076 pubmed publisher
Zhao J, Lu P, Wan C, Huang Y, Cui M, Yang X, et al. Cell-fate transition and determination analysis of mouse male germ cells throughout development. Nat Commun. 2021;12:6839 pubmed publisher
Goh W, Scheer S, Jackson J, Hediyeh Zadeh S, Delconte R, Schuster I, et al. Hhex Directly Represses BIM-Dependent Apoptosis to Promote NK Cell Development and Maintenance. Cell Rep. 2020;33:108285 pubmed publisher
Genga R, Kernfeld E, Parsi K, Parsons T, Ziller M, Maehr R. Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development. Cell Rep. 2019;27:708-718.e10 pubmed publisher
product information
master code :
MAB83771
SKU :
MAB83771-100
product name :
Human/Mouse/Rat HHEX Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse/Rat HHEX Antibody from R&D Systems is a rabbit monoclonal antibody to HHEX. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat HHEX Antibody has been validated for the following applications: Western Blot,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry,Flow Cytometry.
target :
HHEX
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
2018B
conjugate :
Unconjugated
host :
Rabbit
immunogen :
E. coli -derived recombinant human HHEX, Thr111-Gly270, Accession # Q03014
isotype :
IgG
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat
specificity :
Detects human HHEX in direct ELISAs and Western blots.
top caption :
Detection of Human, Mouse, and Rat HHEX antibody by Western Blot.
accessionNumbers :
Q03014
applications :
Western Blot,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry,Flow Cytometry
extended description :
Recombinant Monoclonal Antibody.
USD :
479 USD
product details :
Recombinant Monoclonal Antibody.
alt names :
hematopoietically expressed homeobox, Hex, HEXHMPH, HMPH, Homeobox protein HEX, Homeobox protein PRH, HOX11L-PEN, PRH, PRHhematopoietically-expressed homeobox protein HHEX, PRHX, PRHXhomeobox, hematopoietically expressed, proline-rich homeodomain-containing transcription factor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.