Human Caspase-9 Antibody | R&D Systems MAB8301 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Caspase-9 Antibody

catalog :

MAB8301

quantity :

100 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

LAP6

reactivity :

human

application :

western blot, immunohistochemistry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Mohammadhosseinpour S, Weaver A, Sudhakaran M, Ho L, Le T, Doseff A, et al. Arachidin-1, a Prenylated Stilbenoid from Peanut, Enhances the Anticancer Effects of Paclitaxel in Triple-Negative Breast Cancer Cells. Cancers (Basel). 2023;15: pubmed publisher
Mohammadhosseinpour S, Ho L, Fang L, Xu J, Medina Bolivar F. Arachidin-1, a Prenylated Stilbenoid from Peanut, Induces Apoptosis in Triple-Negative Breast Cancer Cells. Int J Mol Sci. 2022;23: pubmed publisher
Braunstein I, Engelman R, Yitzhaki O, Ziv T, Galardon E, Benhar M. Opposing effects of polysulfides and thioredoxin on apoptosis through caspase persulfidation. J Biol Chem. 2020;295:3590-3600 pubmed publisher
Wobst H, Delsing L, Brandon N, Moss S. Truncation of the TAR DNA-binding protein 43 is not a prerequisite for cytoplasmic relocalization, and is suppressed by caspase inhibition and by introduction of the A90V sequence variant. PLoS ONE. 2017;12:e0177181 pubmed publisher
Seiter M, Salcher S, Rupp M, Hagenbuchner J, Kiechl Kohlendorfer U, Mortier J, et al. Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP). FEBS Open Bio. 2014;4:659-71 pubmed publisher
Karki P, Seong C, Kim J, Hur K, Shin S, Lee J, et al. Intracellular K(+) inhibits apoptosis by suppressing the Apaf-1 apoptosome formation and subsequent downstream pathways but not cytochrome c release. Cell Death Differ. 2007;14:2068-75 pubmed
Stankiewicz A, Lachapelle G, Foo C, Radicioni S, Mosser D. Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation. J Biol Chem. 2005;280:38729-39 pubmed
Straszewski Chavez S, Abrahams V, Funai E, Mor G. X-linked inhibitor of apoptosis (XIAP) confers human trophoblast cell resistance to Fas-mediated apoptosis. Mol Hum Reprod. 2004;10:33-41 pubmed

product information

master code :

MAB8301

SKU :

MAB8301

product name :

Human Caspase-9 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Caspase-9 Antibody from R&D Systems is a mouse monoclonal antibody to Caspase-9. This antibody reacts with human. The Human Caspase-9 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Simple Western.

target :

Caspase-9

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

LAP6

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human Caspase-9, aa 1-134

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Caspase-9 in Western blots and captures Caspase-9 complexed with APAF-1.

gene symbol :

CASP9

top caption :

Capture of Human Caspase-9 and Human Caspase-9 complexed with APAF-1 detected by Western Blot.

applications :

Western Blot,Immunohistochemistry,Simple Western

USD :

439 USD

alt names :

APAF-3APAF3, apoptotic protease activating factor 3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP9, CASP-9, caspase 9, apoptosis-related cysteine peptidase, caspase-9, Caspase9, EC 3.4.22.62, ICE-LAP6CASPASE-9c, ICE-like apoptotic protease 6, MCH6apoptosis-related cysteine protease

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage