product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Bcl-2 Minus C-Terminus Antibody
catalog :
MAB827
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
118701
reactivity :
human, bovine
application :
western blot, immunocytochemistry
more info or order :
citations: 6
Reference
Chou C, Hung C, Chiu C, Tan X, Chen M, Chen C, et al. Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination. Nat Commun. 2023;14:6569 pubmed publisher
Mabrouk Zayed M, Sahyon H, Hanafy N, El Kemary M. The Effect of Encapsulated Apigenin Nanoparticles on HePG-2 Cells through Regulation of P53. Pharmaceutics. 2022;14: pubmed publisher
Nguyen T, Shang E, Shu C, Kim S, Mela A, Humala N, et al. Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma. Nat Commun. 2021;12:5203 pubmed publisher
Shang E, Nguyen T, Shu C, Westhoff M, Karpel Massler G, Siegelin M. Epigenetic Targeting of Mcl-1 Is Synthetically Lethal with Bcl-xL/Bcl-2 Inhibition in Model Systems of Glioblastoma. Cancers (Basel). 2020;12: pubmed publisher
Lu J, Yang J, Burns A, Chen H, Tang D, Walterscheid J, et al. Mediation of electronegative low-density lipoprotein signaling by LOX-1: a possible mechanism of endothelial apoptosis. Circ Res. 2009;104:619-27 pubmed publisher
Ghosh J, Shenoy A, Clark J. Interactions between important regulatory proteins and human alphaB crystallin. Biochemistry. 2007;46:6308-17 pubmed
product information
master code :
MAB827
SKU :
MAB827
product name :
Human Bcl-2 Minus C-Terminus Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Bcl-2 Minus C-Terminus Antibody from R&D Systems is a mouse monoclonal antibody to Bcl-2. This antibody reacts with bovine,human. The Human Bcl-2 Minus C-Terminus Antibody has been validated for the following applications: ELISA-Based Protein Pin Array,Western Blot,Simple Western,Immunocytochemistry.
target :
Bcl-2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
118701
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human Bcl-2 minus the carboxyl-terminal mitochondrial targeting sequence, Met1-Asp211, Accession # P10415
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Bovine,Human
specificity :
Detects human Bcl-2 in Western blots.
gene symbol :
BCL2
top caption :
Detection of Human Bcl-2 Minus C-Terminus antibody by Western Blot.
accessionNumbers :
P10415
applications :
ELISA-Based Protein Pin Array,Western Blot,Simple Western,Immunocytochemistry
USD :
499 USD
alt names :
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl2, Bcl-2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.