Human/Mouse XIAP Antibody | R&D Systems MAB822 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse XIAP Antibody

catalog :

MAB822

quantity :

100 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

117320

reactivity :

human, mouse

application :

western blot

more info or order :

R&D Systems product webpage

citations: 9

Reference
Ono H, Sowa Y, Horinaka M, Iizumi Y, Watanabe M, Morita M, et al. The histone deacetylase inhibitor OBP-801 and eribulin synergistically inhibit the growth of triple-negative breast cancer cells with the suppression of survivin, Bcl-xL, and the MAPK pathway. Breast Cancer Res Treat. 2018;171:43-52 pubmed publisher
Gradzka S, Thomas O, Kretz O, Haimovici A, Vasilikos L, Wong W, et al. Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes. Cell Death Dis. 2018;9:529 pubmed publisher
Dey A, Xiong X, Crim A, Dwivedi S, Mustafi S, Mukherjee P, et al. Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer. Mol Cancer Ther. 2018;17:39-49 pubmed publisher
Ono H, Iizumi Y, Goi W, Sowa Y, Taguchi T, Sakai T. Ribosomal protein S3 regulates XIAP expression independently of the NF-?B pathway in breast cancer cells. Oncol Rep. 2017;38:3205-3210 pubmed publisher
Wang C, Zhang F, Cao Y, Zhang M, Wang A, Xu M, et al. Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress. Sci Rep. 2016;6:34330 pubmed publisher
Umemori Y, Kuribayashi K, Nirasawa S, Kondoh T, Tanaka M, Kobayashi D, et al. Protein kinase C ? regulates survivin expression and inhibits apoptosis in colon cancer. Int J Oncol. 2014;45:1043-50 pubmed publisher
Matte I, Lane D, Boivin M, Rancourt C, Piche A. MUC16 mucin (CA125) attenuates TRAIL-induced apoptosis by decreasing TRAIL receptor R2 expression and increasing c-FLIP expression. BMC Cancer. 2014;14:234 pubmed publisher
Yang S, Wang B, Humphries F, Jackson R, Healy M, Bergin R, et al. Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis. Nat Immunol. 2013;14:927-36 pubmed publisher
Schoenmann Z, Assa Kunik E, Tiomny S, Minis A, Haklai Topper L, Arama E, et al. Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals. J Neurosci. 2010;30:6375-86 pubmed publisher

product information

master code :

MAB822

SKU :

MAB822

product name :

Human/Mouse XIAP Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse XIAP Antibody from R&D Systems is a mouse monoclonal antibody to XIAP. This antibody reacts with human,mouse. The Human/Mouse XIAP Antibody has been validated for the following applications: Western Blot,Knockout Validated.

target :

XIAP

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

117320

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human XIAP, Met1-Ser497, Accession # P98170

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human and mouse XIAP in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) cIAP-1 or rhcIAP-2 is observed.

gene symbol :

XIAP

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human/Mouse XIAP antibody by Western Blot.

accessionNumbers :

P98170

applications :

Western Blot,Knockout Validated

USD :

439 USD

alt names :

API3X-linked inhibitor of apoptosis protein, apoptosis inhibitor 3, baculoviral IAP repeat-containing 4, baculoviral IAP repeat-containing protein 4, BIRC4, BIRC4XLP2, E3 ubiquitin-protein ligase XIAP, EC 6.3.2.-, hIAP3, hIAP-3, hILP, IAP3, IAP-3, IAP-like protein, ILP, ILP1, Inhibitor of apoptosis protein 3, MIHA, X-linked IAP, X-linked inhibitor of apoptosis

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage