Human Flt-3/Flk-2 Antibody | R&D Systems MAB812-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Flt-3/Flk-2 Antibody

catalog :

MAB812-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

66903

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 4

Reference
Yamawaki K, Shiina I, Murata T, Tateyama S, Maekawa Y, Niwa M, et al. FLT3-ITD transduces autonomous growth signals during its biosynthetic trafficking in acute myelogenous leukemia cells. Sci Rep. 2021;11:22678 pubmed publisher
Larrue C, Saland E, Boutzen H, Vergez F, David M, Joffre C, et al. Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML cells. Blood. 2016;127:882-92 pubmed publisher
Köthe S, Müller J, Böhmer S, Tschongov T, Fricke M, Koch S, et al. Features of Ras activation by a mislocalized oncogenic tyrosine kinase: FLT3 ITD signals through K-Ras at the plasma membrane of acute myeloid leukemia cells. J Cell Sci. 2013;126:4746-55 pubmed publisher
Williams A, Li L, Nguyen B, Brown P, Levis M, Small D. Fluvastatin inhibits FLT3 glycosylation in human and murine cells and prolongs survival of mice with FLT3/ITD leukemia. Blood. 2012;120:3069-79 pubmed publisher

product information

master code :

MAB812

SKU :

MAB812-100

product name :

Human Flt-3/Flk-2 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human Flt-3/Flk-2 Antibody from R&D Systems is a mouse monoclonal antibody to Flt-3/Flk-2/CD135. This antibody reacts with human,mouse. The Human Flt-3/Flk-2 Antibody has been validated for the following applications: Immunocytochemistry,Immunoprecipitation,Western Blot,Flow Cytometry,CyTOF-ready.

target :

Flt-3/Flk-2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

66903

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Flt-3/Flk-2, Asn27-Asn541, Accession # AAA18947

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human,Mouse

specificity :

Detect human Flt-3/Flk-2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse Flt-3, recombinant human (rh) SCF R, rhPDGF R alpha , or rhPDGF R▀ is observed.

gene symbol :

FLT3

accessionNumbers :

AAA18947

applications :

Immunoprecipitation,Western Blot,Immunocytochemistry,Flow Cytometry,CyTOF-ready

USD :

469 USD

alt names :

CD135, CD135 antigen, EC 2.7.10, fetal liver kinase 2, FL cytokine receptor, Flk-2, FLK2, Flt3, FLT-3, FLT3 receptor tyrosine kinase, Fms-like tyrosine kinase 3, fms-related tyrosine kinase 3, growth factor receptor tyrosine kinase type III, Stem cell tyrosine kinase 1, STK-1, STK1EC 2.7.10.1, Tyrosine-protein kinase receptor FLT3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage