Human BMPR-II Antibody | R&D Systems MAB811-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human BMPR-II Antibody

catalog :

MAB811-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

73805

reactivity :

human, rat

application :

western blot, immunocytochemistry, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 5

Reference
Veschi V, Mangiapane L, Nicotra A, Di Franco S, Scavo E, Apuzzo T, et al. Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant. Oncogene. 2020;39:987-1003 pubmed publisher
Hurst L, Dunmore B, Long L, Crosby A, Al Lamki R, Deighton J, et al. TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling. Nat Commun. 2017;8:14079 pubmed publisher
Chaverneff F, Barrett J. Casein kinase II contributes to the synergistic effects of BMP7 and BDNF on Smad 1/5/8 phosphorylation in septal neurons under hypoglycemic stress. J Neurochem. 2009;109:733-43 pubmed publisher
Sengle G, Ono R, Lyons K, Bachinger H, Sakai L. A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7. J Mol Biol. 2008;381:1025-39 pubmed publisher
Dai J, Keller J, Zhang J, Lu Y, Yao Z, Keller E. Bone morphogenetic protein-6 promotes osteoblastic prostate cancer bone metastases through a dual mechanism. Cancer Res. 2005;65:8274-85 pubmed

product information

master code :

MAB811

SKU :

MAB811-100

product name :

Human BMPR-II Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human BMPR-II Antibody from R&D Systems is a mouse monoclonal antibody to BMPR-II. This antibody reacts with human,rat. The Human BMPR-II Antibody has been validated for the following applications: ELISA Development,Immunoprecipitation,Western Blot,Immunocytochemistry.

target :

BMPR-II

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

73805

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human BMPR-II, Ala26-Ile151, Accession # Q13873

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Rat

specificity :

Detects human BMPR-II in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human (rh) BMP R-IA or rhBMPR-IB.

gene symbol :

BMPR2

accessionNumbers :

Q13873

applications :

ELISA Development,Immunoprecipitation,Western Blot,Immunocytochemistry

USD :

459 USD

alt names :

BMP type II receptor, BMP type-2 receptor, BMPR2, BMPR-2, BMPR3, BMPRII, BMPR-IIprimary pulmonary hypertension 1, Bone morphogenetic protein receptor type II, bone morphogenetic protein receptor type-2, bone morphogenetic protein receptor, type II (serine/threonine kinase), BRK-3, EC 2.7.11, EC 2.7.11.30, FLJ41585, FLJ76945, PPH1BMR2, T-ALK, type II activin receptor-like kinase, type II receptor for bone morphogenetic protein-4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage