product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Lgr5/GPR49 Antibody
catalog :
MAB8078
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
707042
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Reference
Cadamuro F, Marongiu L, Marino M, Tamini N, Nespoli L, Zucchini N, et al. 3D bioprinted colorectal cancer models based on hyaluronic acid and signalling glycans. Carbohydr Polym. 2023;302:120395 pubmed publisher
Roudebush C, Cátala Valentin A, Andl T, Le Bras G, Andl C. Activin A-mediated epithelial de-differentiation contributes to injury repair in an in vitro gastrointestinal reflux model. Cytokine. 2019;123:154782 pubmed publisher
Chiou G, Yang T, Huang C, Tang C, Yen J, Tsai M, et al. Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells. Sci Rep. 2017;7:2172 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB8078
SKU :
MAB8078
product name :
Human Lgr5/GPR49 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human Lgr5/GPR49 Antibody from R&D Systems is a mouse monoclonal antibody to Lgr5/GPR49. This antibody reacts with human. The Human Lgr5/GPR49 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Flow Cytometry,Agonist Activity,Immunocytochemistry,CyTOF-ready.
target :
Lgr5/GPR49
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
707042
conjugate :
Unconjugated
dilution :
Flow Cytometry 2.5 ug/10^6 cells, Agonist Activity, Immunocytochemistry 8-25 ug/mL, CyTOF-ready
host :
Mouse
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant human Lgr5/GPR49, Met1-Ile560, Accession # O75473
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Lgr5/GPR49 in ELISA. Stains human and mouse Lgr5 transfected cells but not irrelevant transfectants in Flow Cytometry and Immunocytochemistry. This antibody, also known as "RD42", has been found to detect an epitope in C-terminal LRR cap of LGR5 (Ref. 1).
gene symbol :
LGR5
top caption :
Detection of Lgr5/GPR49 antibody in NS0 Mouse Cell Line Transfected with Human Lgr5/GPR49 and eGFP antibody by Flow Cytometry.
accessionNumbers :
O75473
applications :
Flow Cytometry,Agonist Activity,Immunocytochemistry,CyTOF-ready,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin
extended description :
Published as Clone RD42
USD :
489 USD
product details :
Published as Clone RD42
alt names :
FEX, G protein-coupled receptor 49, GPR49, GPR49G-protein coupled receptor HG38, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67, GRP49, HG38, leucine-rich repeat containing G protein-coupled receptor 5, leucine-rich repeat-containing G protein-coupled receptor 5, leucine-rich repeat-containing G-protein coupled receptor 5, MGC117008, orphan G protein-coupled receptor HG38
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.