product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
Human Osteoprotegerin/TNFRSF11B Antibody
catalog :
MAB8051-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
69127
reactivity :
human
application :
ELISA, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 8
Reference
Giovannini S, Tinelli G, Biscetti F, Straface G, Angelini F, Pitocco D, et al. Serum high mobility group box-1 and osteoprotegerin levels are associated with peripheral arterial disease and critical limb ischemia in type 2 diabetic subjects. Cardiovasc Diabetol. 2017;16:99 pubmed publisher
Djamiatun K, van der Ven A, de Groot P, Faradz S, Hapsari D, Dolmans W, et al. Severe dengue is associated with consumption of von Willebrand factor and its cleaving enzyme ADAMTS-13. PLoS Negl Trop Dis. 2012;6:e1628 pubmed publisher
Liu Y, Wang T, Yan J, Jiagbogu N, Heideman D, Canfield A, et al. HGF/c-Met signalling promotes Notch3 activation and human vascular smooth muscle cell osteogenic differentiation in vitro. Atherosclerosis. 2011;219:440-7 pubmed publisher
Zinonos I, Labrinidis A, Lee M, Liapis V, Hay S, Ponomarev V, et al. Anticancer efficacy of Apo2L/TRAIL is retained in the presence of high and biologically active concentrations of osteoprotegerin in vivo. J Bone Miner Res. 2011;26:630-43 pubmed publisher
Hu H, Kwun J, Aizenstein B, Knechtle S. Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation. 2009;87:1814-20 pubmed publisher
Harding G, Mak Y, Evans B, Cheung J, MacDonald D, Hampson G. The effects of dexamethasone and dehydroepiandrosterone (DHEA) on cytokines and receptor expression in a human osteoblastic cell line: potential steroid-sparing role for DHEA. Cytokine. 2006;36:57-68 pubmed
Cross S, Yang Z, Brown N, Balasubramanian S, Evans C, Woodward J, et al. Osteoprotegerin (OPG)--a potential new role in the regulation of endothelial cell phenotype and tumour angiogenesis?. Int J Cancer. 2006;118:1901-8 pubmed
Mandelin J, Li T, Hukkanen M, Liljeström M, Salo J, Santavirta S, et al. Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K. J Rheumatol. 2005;32:713-20 pubmed
product information
master code :
MAB8051
SKU :
MAB8051-100
product name :
Human Osteoprotegerin/TNFRSF11B Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human Osteoprotegerin/TNFRSF11B Antibody from R&D Systems is a mouse monoclonal antibody to Osteoprotegerin/TNFRSF11B. This antibody reacts with human. The Human Osteoprotegerin/TNFRSF11B Antibody has been validated for the following applications: Immunoprecipitation,ELISA Capture,Immunocytochemistry,Antibody Array Development,ELISA Development,ELISA Development (Capture),Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair).
target :
Osteoprotegerin/TNFRSF11B
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
69127
conjugate :
Unconjugated
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Osteoprotegerin/TNFRSF11B, Glu22-Leu401, Accession # O00300
isotype :
IgG2a
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human Osteoprotegerin/TNFRSF11B in ELISAs. It has been reported (1), and R D Systems testing has confirmed, that this antibody shows strong cross-reactivity with an unrelated protein, human Carbonic Anhydrase II. In Western blots, this antibody does not cross-react with recombinant human (rh) 4-1BB, rhCD27, rhCD30, recombinant mouse (rm) CD30, rmCD40, rhDR3, rhDR6, rhFas, rmFas, rhGITR, rmGITR, rhHVEM, rhLT▀R, rhNGF R, rmOPG, rhTNF RI, rmTNF RI, rhTNF RII, or rmTNF RII.
gene symbol :
TNFRSF11B
accessionNumbers :
O00300
applications :
Immunocytochemistry,Antibody Array Development,ELISA Development,ELISA Development (Capture),Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair)
USD :
459 USD
alt names :
OCIF, OCIFMGC29565, OPG, OPGtumor necrosis factor receptor superfamily member 11B, Osteoclastogenesis inhibitory factor, Osteoprotegerin, TNFRSF11B, TR1, tumor necrosis factor receptor superfamily, member 11b
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.