Human HOIP/RNF31 Antibody | R&D Systems MAB8039 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human HOIP/RNF31 Antibody

catalog :

MAB8039

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

875227

reactivity :

human

application :

western blot, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 8

Reference
Zhang Z, Kong X, Ligtenberg M, van Hal van Veen S, Visser N, de Bruijn B, et al. RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells. Cell Rep Med. 2022;3:100655 pubmed publisher
Bedsaul J, Shah N, Hutcherson S, Pomerantz J. Mechanistic impact of oligomer poisoning by dominant-negative CARD11 variants. iScience. 2022;25:103810 pubmed publisher
Yin H, Karayel Ö, Chao Y, Seeholzer T, Hamp I, Plettenburg O, et al. A20 and ABIN-1 cooperate in balancing CBM complex-triggered NF-κB signaling in activated T cells. Cell Mol Life Sci. 2022;79:112 pubmed publisher
Tang C, Yang J, Liu Z, Chen Y, Zeng C. Taraxasterol acetate targets RNF31 to inhibit RNF31/p53 axis-driven cell proliferation in colorectal cancer. Cell Death Discov. 2021;7:66 pubmed publisher
Douglas T, Saleh M. Post-translational Modification of OTULIN Regulates Ubiquitin Dynamics and Cell Death. Cell Rep. 2019;29:3652-3663.e5 pubmed publisher
Zhu F, Yi G, Liu X, Zhu F, Zhao A, Wang A, et al. Ring finger protein 31-mediated atypical ubiquitination stabilizes forkhead box P3 and thereby stimulates regulatory T-cell function. J Biol Chem. 2018;293:20099-20111 pubmed publisher
de Jong M, Liu Z, Chen D, Alto N. Shigella flexneri suppresses NF-?B activation by inhibiting linear ubiquitin chain ligation. Nat Microbiol. 2016;1:16084 pubmed publisher
Schlicher L, Wissler M, Preiss F, Brauns Schubert P, Jakob C, Dumit V, et al. SPATA2 promotes CYLD activity and regulates TNF-induced NF-?B signaling and cell death. EMBO Rep. 2016;17:1485-1497 pubmed

product information

brand :

R&D Systems

master code :

MAB8039

SKU :

MAB8039

product name :

Human HOIP/RNF31 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human HOIP/RNF31 Antibody from R&D Systems is a mouse monoclonal antibody to HOIP/RNF31. This antibody reacts with human. The Human HOIP/RNF31 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunocytochemistry,Simple Western.

target :

HOIP/RNF31

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

875227

conjugate :

Unconjugated

dilution :

Western Blot 0.5 ug/mL, Simple Western 5 ug/mL, Immunocytochemistry 8-25 ug/mL

host :

Mouse

immunogen :

E. coli -derived recombinant human HOIP/RNF31, Arg970-Lys1072, Accession # Q96EP0

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human HOIP/RNF31 in direct ELISA and Western Blot.

gene symbol :

RNF31

top caption :

Detection of Human HOIP/RNF31 antibody by Western Blot.

accessionNumbers :

Q96EP0

applications :

Simple Western,Flow Cytometry,Western Blot,Immunocytochemistry

USD :

469 USD

alt names :

EC 6.3.2.-, FLJ10111, FLJ23501, HOIP, MGC19975, ring finger protein 31, RNF31, ZIBRA, ZIBRAHOIL-1-interacting protein, Zinc in-between-RING-finger ubiquitin-associated domain protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage