Human/Mouse/Rat p62/SQSTM1 Antibody | R&D Systems MAB8028 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat p62/SQSTM1 Antibody

catalog :

MAB8028

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

864807

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 19

Reference
dos Santos C, Cambraia A, Shrestha S, Cutler M, Cottam M, Perkins G, et al. Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity in mice. Nat Commun. 2024;15:9063 pubmed publisher
Ayoubi R, Alshafie W, Shlaifer I, Southern K, McPherson P, Laflamme C. The identification of high-performing antibodies for Sequestosome-1 for use in Western blot, immunoprecipitation and immunofluorescence. F1000Res. 2023;12:324 pubmed publisher
Fang L, Chen W, Jaksch P, Molino A, Saglia A, Roth M, et al. Treprostinil Reconstitutes Mitochondrial Organisation and Structure in Idiopathic Pulmonary Fibrosis Cells. Int J Mol Sci. 2023;24: pubmed publisher
Barcena M, Tonini G, Haritonow N, Breiter P, Milting H, Baczkó I, et al. Sex and age differences in AMPK phosphorylation, mitochondrial homeostasis, and inflammation in hearts from inflammatory cardiomyopathy patients. Aging Cell. 2023;22:e13894 pubmed publisher
Mohammed S, Thadathil N, Ohene Marfo P, Tran A, Van Der Veldt M, Georgescu C, et al. Absence of Either Ripk3 or Mlkl Reduces Incidence of Hepatocellular Carcinoma Independent of Liver Fibrosis. Mol Cancer Res. 2023;21:933-946 pubmed publisher
Mitsui K, Hishiyama S, Jain A, Kotoda Y, Abe M, Matsukawa T, et al. Role of macrophage autophagy in postoperative pain and inflammation in mice. J Neuroinflammation. 2023;20:102 pubmed publisher
Fang L, Zhang M, Li J, Zhou L, Tamm M, Roth M. Airway Smooth Muscle Cell Mitochondria Damage and Mitophagy in COPD via ERK1/2 MAPK. Int J Mol Sci. 2022;23: pubmed publisher
Scotece M, Vaamonde Garc xed a C, Lechuga Vieco A, Cort xe9 s A, G xf3 mez M, Filgueira Fern xe1 ndez P, et al. mtDNA variability determines spontaneous joint aging damage in a conplastic mouse model. Aging (Albany NY). 2022;14:5966-5983 pubmed publisher
Guo Y, Chomiak A, Hong Y, Lowe C, Kopsidas C, Chan W, et al. Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration. iScience. 2022;25:104519 pubmed publisher
Zhao K, Schäfer A, Zhang Z, Elsässer K, Culmsee C, Zhong L, et al. Inhibition of Carbonic Anhydrase 2 Overcomes Temozolomide Resistance in Glioblastoma Cells. Int J Mol Sci. 2021;23: pubmed publisher
Larsen L, van den Boogert M, Rios Ocampo W, Jansen J, Conlon D, Chong P, et al. Defective Lipid Droplet-Lysosome Interaction Causes Fatty Liver Disease as Evidenced by Human Mutations in TMEM199 and CCDC115. Cell Mol Gastroenterol Hepatol. 2021;13:583-597 pubmed publisher
Mergenthaler P, Hariharan S, Pemberton J, Lourenco C, Penn L, Andrews D. Rapid 3D phenotypic analysis of neurons and organoids using data-driven cell segmentation-free machine learning. PLoS Comput Biol. 2021;17:e1008630 pubmed publisher
Yun E, Kim S, Hsieh J, Baek S. Wnt/β-catenin signaling pathway induces autophagy-mediated temozolomide-resistance in human glioblastoma. Cell Death Dis. 2020;11:771 pubmed publisher
Perez Vidakovics M, Ure A, Arrías P, Romanowski V, Gomez R. Junín virus induces autophagy in human A549 cells. PLoS ONE. 2019;14:e0218730 pubmed publisher
Walker D, Tang T, Lue L. Increased expression of toll-like receptor 3, an anti-viral signaling molecule, and related genes in Alzheimer's disease brains. Exp Neurol. 2018;309:91-106 pubmed publisher
Ehrnhoefer D, Martin D, Schmidt M, Qiu X, Ladha S, Caron N, et al. Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease. Acta Neuropathol Commun. 2018;6:16 pubmed publisher
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Saleem S, Biswas S. Tribbles Pseudokinase 3 Induces Both Apoptosis and Autophagy in Amyloid-Î²-induced Neuronal Death. J Biol Chem. 2017;292:2571-2585 pubmed publisher

product information

master code :

MAB8028

SKU :

MAB8028

product name :

Human/Mouse/Rat p62/SQSTM1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat p62/SQSTM1 Antibody from R&D Systems is a mouse monoclonal antibody to p62/SQSTM1. This antibody reacts with human,mouse,rat,transgenic mouse. The Human/Mouse/Rat p62/SQSTM1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunoprecipitation,Immunocytochemistry,Simple Western,Knockout Validated.

target :

p62/SQSTM1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

864807

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human p62/SQSTM1, Asp368-Leu440, Accession # Q13501

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects human p62/SQSTM1 in ELISAs. Detects human, mouse and rat p62/SQSTM1 in Western blots

gene symbol :

SQSTM1

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human, Mouse, and Rat p62/SQSTM1 antibody by Western Blot.

accessionNumbers :

Q13501

applications :

Western Blot,Immunohistochemistry,Immunoprecipitation,Immunocytochemistry,Simple Western,Knockout Validated

USD :

479 USD

alt names :

A170, Autophagy Receptor P62, DMRV, EBI3-associated protein of 60 kDa, EBI3-associated protein p60, EBIAP, FTDALS3, NADGP, ORCA, OSIL, oxidative stress induced like, p60PDB3, p62, p62B, Paget disease of bone 3, PDB3, phosphotyrosine independent ligand for the Lck SH2 domain p62, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, sequestosome 1, sequestosome-1, SQSTM1, Ubiquitin-binding protein p62, ZIP3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage