Human CXCL13/BLC/BCA-1 Antibody | R&D Systems MAB801 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CXCL13/BLC/BCA-1 Antibody

catalog :

MAB801

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

53610

reactivity :

human

application :

western blot, ELISA, neutralization

citations: 11

Reference
Satou A, Tabata T, Miyoshi H, Kohno K, Suzuki Y, Yamashita D, et al. Methotrexate-associated lymphoproliferative disorders of T-cell phenotype: clinicopathological analysis of 28 cases. Mod Pathol. 2019;: pubmed publisher
Muto R, Miyoshi H, Sato K, Furuta T, Muta H, Kawamoto K, et al. Epidemiology and secular trends of malignant lymphoma in Japan: Analysis of 9426 cases according to the World Health Organization classification. Cancer Med. 2018;7:5843-5858 pubmed publisher
Thommen D, Koelzer V, Herzig P, Roller A, Trefny M, Dimeloe S, et al. A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade. Nat Med. 2018;24:994-1004 pubmed publisher
Aqrawi L, Ivanchenko M, Bjork A, Ramírez Sepúlveda J, Imgenberg Kreuz J, Kvarnstrom M, et al. Diminished CXCR5 expression in peripheral blood of patients with Sjögren's syndrome may relate to both genotype and salivary gland homing. Clin Exp Immunol. 2018;192:259-270 pubmed publisher
Asai A, Tsuchimoto Y, Ohama H, Fukunishi S, Tsuda Y, Kobayashi M, et al. Host antitumor resistance improved by the macrophage polarization in a chimera model of patients with HCC. Oncoimmunology. 2017;6:e1299301 pubmed publisher
Klimatcheva E, Pandina T, Reilly C, Torno S, Bussler H, Scrivens M, et al. CXCL13 antibody for the treatment of autoimmune disorders. BMC Immunol. 2015;16:6 pubmed publisher
Edwards K, Goyal J, Plavina T, Czerkowicz J, Goelz S, Ranger A, et al. Feasibility of the use of combinatorial chemokine arrays to study blood and CSF in multiple sclerosis. PLoS ONE. 2013;8:e81007 pubmed publisher
Panse J, Friedrichs K, Marx A, Hildebrandt Y, Luetkens T, Barrels K, et al. Chemokine CXCL13 is overexpressed in the tumour tissue and in the peripheral blood of breast cancer patients. Br J Cancer. 2008;99:930-8 pubmed publisher
Bürkle A, Niedermeier M, Schmitt Gräff A, Wierda W, Keating M, Burger J. Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia. Blood. 2007;110:3316-25 pubmed
Lisignoli G, Cristino S, Piacentini A, Cavallo C, Caplan A, Facchini A. Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54. J Cell Physiol. 2006;207:364-73 pubmed
Lisignoli G, Cristino S, Toneguzzi S, Grassi F, Piacentini A, Cavallo C, et al. IL1beta and TNFalpha differently modulate CXCL13 chemokine in stromal cells and osteoblasts isolated from osteoarthritis patients: evidence of changes associated to cell maturation. Exp Gerontol. 2004;39:659-65 pubmed

product information

brand :

R&D Systems

master code :

MAB801

SKU :

MAB801-100

product name :

Human CXCL13/BLC/BCA-1 Antibody

description :

The Human CXCL13/BLC/BCA-1 Antibody from R&D Systems is a mouse monoclonal antibody to CXCL13/BLC/BCA-1. This antibody reacts with human. The Human CXCL13/BLC/BCA-1 Antibody has been validated for the following applications: Western Blot, Neutralization, Intracellular Staining by Flow Cytometry, CyTOF-ready, ELISA Capture (Matched Antibody Pair).

target :

CXCL13/BLC/BCA-1

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

53610

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CXCL13/BLC/BCA-1, Val23-Arg94, Accession # O43927

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human CXCL13/BLC/BCA-1 in ELISAs and Western blots. In ELISAs, no cross-reactivity with recombinant human (rh) CXCL1, rhCXCL2, rhCXCL3, rhCXCL8/IL-8, rhCXCL10, rhCXCL9, rhCXCL12/SDF-1 alpha , or rhCXCL12/SDF-1 beta is observed. In Western blots, no cross-reactivity with recombinant mouse CXCL13/BLC/BCA-1 is observed.

gene symbol :

CXCL13

details of functionality :

ActivityAssaywCitation not found None None None None

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB801

accessionNumbers :

O43927

applications :

Western Blot, Neutralization, Intracellular Staining by Flow Cytometry, CyTOF-ready, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

369 USD

alt names :

ANGIE, ANGIE2, B cell-attracting chemokine 1, B lymphocyte chemoattractant, BCA1, BCA-1, BCA1B-cell chemoattractant, BCA-1CXC chemokine BLC, B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1), BLC, BLCSmall-inducible cytokine B13, BLR1L, B-lymphocyte chemoattractant, chemokine (C-X-C motif) ligand 13, chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant), C-X-C motif chemokine 13, SCYB13, SCYB13B-cell-attracting chemokine 1, small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cellchemoattractant)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.