Human CXCL13/BLC/BCA-1 Antibody | R&D Systems MAB801-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CXCL13/BLC/BCA-1 Antibody

catalog :

MAB801-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

53610

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 18

Reference
Samson C, Thiolat A, Moktefi A, Cohen J, Pilon C, Grimbert P. Belatacept inhibit human B cell germinal center development in immunodeficient mice. Sci Rep. 2023;13:13816 pubmed publisher
Chang S, Chao C, Kwan A, Chai C. The Diagnostic Significance of CXCL13 in M2 Tumor Immune Microenvironment of Human Astrocytoma. Pathol Oncol Res. 2022;28:1610230 pubmed publisher
Satou A, Tabata T, Miyoshi H, Kohno K, Suzuki Y, Yamashita D, et al. Methotrexate-associated lymphoproliferative disorders of T-cell phenotype: clinicopathological analysis of 28 cases. Mod Pathol. 2019;: pubmed publisher
Muto R, Miyoshi H, Sato K, Furuta T, Muta H, Kawamoto K, et al. Epidemiology and secular trends of malignant lymphoma in Japan: Analysis of 9426 cases according to the World Health Organization classification. Cancer Med. 2018;7:5843-5858 pubmed publisher
Thommen D, Koelzer V, Herzig P, Roller A, Trefny M, Dimeloe S, et al. A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade. Nat Med. 2018;24:994-1004 pubmed publisher
Aqrawi L, Ivanchenko M, Bjork A, Ramírez Sepúlveda J, Imgenberg Kreuz J, Kvarnstrom M, et al. Diminished CXCR5 expression in peripheral blood of patients with Sjögren's syndrome may relate to both genotype and salivary gland homing. Clin Exp Immunol. 2018;192:259-270 pubmed publisher
Asai A, Tsuchimoto Y, Ohama H, Fukunishi S, Tsuda Y, Kobayashi M, et al. Host antitumor resistance improved by the macrophage polarization in a chimera model of patients with HCC. Oncoimmunology. 2017;6:e1299301 pubmed publisher
Rao D, Gurish M, Marshall J, Slowikowski K, Fonseka C, Liu Y, et al. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 2017;542:110-114 pubmed publisher
Komori M, Lin Y, Cortese I, Blake A, Ohayon J, Cherup J, et al. Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosis. Ann Clin Transl Neurol. 2016;3:166-79 pubmed publisher
Kim S, Ryu K, Hong M, Ko Y, Kim W. The serum CXCL13 level is associated with the Glasgow Prognostic Score in extranodal NK/T-cell lymphoma patients. J Hematol Oncol. 2015;8:49 pubmed publisher
Klimatcheva E, Pandina T, Reilly C, Torno S, Bussler H, Scrivens M, et al. CXCL13 antibody for the treatment of autoimmune disorders. BMC Immunol. 2015;16:6 pubmed publisher
Komori M, Blake A, Greenwood M, Lin Y, Kosa P, Ghazali D, et al. Cerebrospinal fluid markers reveal intrathecal inflammation in progressive multiple sclerosis. Ann Neurol. 2015;78:3-20 pubmed publisher
Edwards K, Goyal J, Plavina T, Czerkowicz J, Goelz S, Ranger A, et al. Feasibility of the use of combinatorial chemokine arrays to study blood and CSF in multiple sclerosis. PLoS ONE. 2013;8:e81007 pubmed publisher
Kitaya K, Yasuo T. Aberrant expression of selectin E, CXCL1, and CXCL13 in chronic endometritis. Mod Pathol. 2010;23:1136-46 pubmed publisher
Panse J, Friedrichs K, Marx A, Hildebrandt Y, Luetkens T, Barrels K, et al. Chemokine CXCL13 is overexpressed in the tumour tissue and in the peripheral blood of breast cancer patients. Br J Cancer. 2008;99:930-8 pubmed publisher
Bürkle A, Niedermeier M, Schmitt Gräff A, Wierda W, Keating M, Burger J. Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia. Blood. 2007;110:3316-25 pubmed
Lisignoli G, Cristino S, Piacentini A, Cavallo C, Caplan A, Facchini A. Hyaluronan-based polymer scaffold modulates the expression of inflammatory and degradative factors in mesenchymal stem cells: Involvement of Cd44 and Cd54. J Cell Physiol. 2006;207:364-73 pubmed
Lisignoli G, Cristino S, Toneguzzi S, Grassi F, Piacentini A, Cavallo C, et al. IL1beta and TNFalpha differently modulate CXCL13 chemokine in stromal cells and osteoblasts isolated from osteoarthritis patients: evidence of changes associated to cell maturation. Exp Gerontol. 2004;39:659-65 pubmed

product information

brand :

R&D Systems

master code :

MAB801

SKU :

MAB801-100

product name :

Human CXCL13/BLC/BCA-1 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human CXCL13/BLC/BCA-1 Antibody from R&D Systems is a mouse monoclonal antibody to CXCL13/BLC/BCA-1. This antibody reacts with human,mouse. The Human CXCL13/BLC/BCA-1 Antibody has been validated for the following applications: Immunohistochemistry,ELISA Development,Immuno-PCR,Flow Cytometry,Western Blot,Direct ELISA,Immunohistochemistry-Paraffin,Immunocytochemistry,Neutralization,ELISA Capture (Matched Antibody Pair).

target :

CXCL13/BLC/BCA-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

53610

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Neutralization 0.3-0.9 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL

host :

Mouse

immunogen :

E. coli -derived recombinant human CXCL13/BLC/BCA-1, Val23-Arg94, Accession # O43927

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human CXCL13/BLC/BCA-1 in ELISAs and Western blots. In ELISAs, no cross-reactivity with recombinant human (rh) CXCL1, rhCXCL2, rhCXCL3, rhCXCL8/IL-8, rhCXCL10, rhCXCL9, rhCXCL12/SDF-1 alpha , or rhCXCL12/SDF-1▀ is observed. In Western blots, no cross-reactivity with recombinant mouse CXCL13/BLC/BCA-1 is observed.

gene symbol :

CXCL13

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Recombinant Human CXCL13/BLC/BCA-1 antibody by Western Blot.

accessionNumbers :

O43927

applications :

Neutralization,ELISA Capture (Matched Antibody Pair),ELISA Development,Immuno-PCR,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Direct ELISA,Immunocytochemistry

USD :

499 USD

alt names :

ANGIE, ANGIE2, B cell-attracting chemokine 1, B lymphocyte chemoattractant, BCA1, BCA-1, BCA1B-cell chemoattractant, BCA-1CXC chemokine BLC, B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1), BLC, BLCSmall-inducible cytokine B13, BLR1L, B-lymphocyte chemoattractant, chemokine (C-X-C motif) ligand 13, chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant), C-X-C motif chemokine 13, SCYB13, SCYB13B-cell-attracting chemokine 1, small inducible cytokine B subfamily (Cys-X-Cys motif), member 13 (B-cellchemoattractant)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage