Mouse IGF-II/IGF2 Antibody | R&D Systems MAB792-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IGF-II/IGF2 Antibody

catalog :

MAB792-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

122404

reactivity :

human, mouse

application :

western blot, ELISA

more info or order :

R&D Systems product webpage

citations: 4

Reference
De Giovanni C, Nanni P, Landuzzi L, Ianzano M, Nicoletti G, Croci S, et al. Immune targeting of autocrine IGF2 hampers rhabdomyosarcoma growth and metastasis. BMC Cancer. 2019;19:126 pubmed publisher
Peng J, Dalton J, BUTT M, Tracy K, Kennedy D, Haroldsen P, et al. Reveglucosidase alfa (BMN 701), an IGF2-Tagged rhAcid ?-Glucosidase, Improves Respiratory Functional Parameters in a Murine Model of Pompe Disease. J Pharmacol Exp Ther. 2017;360:313-323 pubmed publisher
Ostrovsky O, Ahmed N, Argon Y. The chaperone activity of GRP94 toward insulin-like growth factor II is necessary for the stress response to serum deprivation. Mol Biol Cell. 2009;20:1855-64 pubmed publisher
Yin D, Vreeland F, Schaaf L, Millham R, Duncan B, Sharma A. Clinical pharmacodynamic effects of the growth hormone receptor antagonist pegvisomant: implications for cancer therapy. Clin Cancer Res. 2007;13:1000-9 pubmed

product information

master code :

MAB792

SKU :

MAB792-100

product name :

Mouse IGF-II/IGF2 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Mouse IGF-II/IGF2 Antibody from R&D Systems is a rat monoclonal antibody to IGF-II/IGF2. This antibody reacts with human,mouse. The Mouse IGF-II/IGF2 Antibody has been validated for the following applications: ELISA Capture,ELISA Development,Western Blot,Functional Assay,ELISA Capture (Matched Antibody Pair).

target :

IGF-II/IGF2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

122404

conjugate :

Unconjugated

host :

Rat

immunogen :

E. coli -derived recombinant mouse IGF-II/IGF2, Ala25-Glu91, Accession # P09535

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects mouse IGF-II/IGF2 in ELISAs and Western blots. In ELISAs, this antibody shows less than 6% cross-reactivity with recombinant human (rh) IGF-I R and no cross-reactivity with rhIGF-I and rmIGF-I is observed. In Western blots, 100% cross-reactivity with rhIGF-II and no cross reactivity with rmIGF-I is observed.

gene symbol :

IGF2

top caption :

Detection of Recombinant Human and Mouse IGF-II/IGF2 antibody by Western Blot.

accessionNumbers :

P09535

applications :

ELISA Development,Western Blot,Functional Assay,ELISA Capture (Matched Antibody Pair)

USD :

459 USD

alt names :

C11orf43, chromosome 11 open reading frame 43, FLJ22066, FLJ44734, GRDF, IGF2, IGF-2, IGFII, IGF-II, insulin-like growth factor 2 (somatomedin A), insulin-like growth factor II, insulin-like growth factor type 2, MSA, PEG2, PP9974, somatomedin-A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage