product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse IGF-I/IGF-1 Antibody
catalog :
MAB791-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
489 USD
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
126002
reactivity :
human, mouse
application :
western blot, ELISA, neutralization
more info or order :
citations: 7
Reference
Moon P, Kim M, Oh H, Nam S, Han N, Jeong H, et al. Cysteine induces longitudinal bone growth in mice by upregulating IGF-I. Int J Mol Med. 2015;36:571-6 pubmed publisher
Steger J, Füller E, Garcia Cuellar M, Hetzner K, Slany R. Insulin-like growth factor 1 is a direct HOXA9 target important for hematopoietic transformation. Leukemia. 2015;29:901-8 pubmed publisher
Fletcher L, Isgor E, Sprague S, Williams L, Alajajian B, Jimenez D, et al. Spatial distribution of insulin-like growth factor binding protein-2 following hypoxic-ischemic injury. BMC Neurosci. 2013;14:158 pubmed publisher
Fritz J, Dwyer Nield L, Malkinson A. Stimulation of neoplastic mouse lung cell proliferation by alveolar macrophage-derived, insulin-like growth factor-1 can be blocked by inhibiting MEK and PI3K activation. Mol Cancer. 2011;10:76 pubmed publisher
Mehta H, Gao Q, Galet C, Paharkova V, Wan J, Said J, et al. IGFBP-3 is a metastasis suppression gene in prostate cancer. Cancer Res. 2011;71:5154-63 pubmed publisher
Yamada P, Mehta H, Hwang D, Roos K, Hevener A, Lee K. Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation. Endocrinology. 2010;151:5741-50 pubmed publisher
Raina K, Blouin M, Singh R, Majeed N, Deep G, Varghese L, et al. Dietary feeding of silibinin inhibits prostate tumor growth and progression in transgenic adenocarcinoma of the mouse prostate model. Cancer Res. 2007;67:11083-91 pubmed
product information
master code :
MAB791
SKU :
MAB791-100
product name :
Mouse IGF-I/IGF-1 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Mouse IGF-I/IGF-1 Antibody from R&D Systems is a hamster monoclonal antibody to IGF-I/IGF-1. This antibody reacts with mouse. The Mouse IGF-I/IGF-1 Antibody has been validated for the following applications: ELISA Development,ELISA Development (Capture),Western Blot,Neutralization,ELISA Capture (Matched Antibody Pair).
target :
IGF-I/IGF-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
126002
conjugate :
Unconjugated
host :
Hamster
immunogen :
E. coli -derived recombinant mouse IGF-I/IGF-1, Gly49-Ala118, Accession # P05017
isotype :
IgG
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse IGF-I/IGF-1 in direct ELISAs and Western blots. In ELISAs, no cross-reactivity with recombinant human IGF-I/IGF-1, recombinant mouse (rm) IGF-II/IGF-2, rmIGFBP-2, rmIGFBP-5, or rmIGFBP-6 is observed.
gene symbol :
IGF1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by IGF-I/IGF-1 and Neutralization by Mouse IGF-I/IGF-1 Antibody.
accessionNumbers :
P05017
applications :
ELISA Development,ELISA Development (Capture),Western Blot,Neutralization,ELISA Capture (Matched Antibody Pair)
USD :
489 USD
alt names :
IBP1, IGF1, IGF-1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, Somatomedin A, Somatomedin C, Somatomedin-C
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.