product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TIGIT Antibody
catalog :
MAB7898
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
741182
reactivity :
human
application :
neutralization, flow cytometry
more info or order :
R&D Systems product webpage
citations: 3
Reference
Calvet Mirabent M, S xe1 nchez Cerrillo I, Mart xed n C xf3 freces N, Mart xed nez Fleta P, de la Fuente H, Tsukalov I, et al. Antiretroviral therapy duration and immunometabolic state determine efficacy of ex vivo dendritic cell-based treatment restoring functional HIV-specific CD8+ T cells in people living with HIV. EBioMedicine. 2022;81:104090 pubmed publisher
Martinez M, Kim S, St Jean N, O Brien S, Lian L, Sun J, et al. Addition of anti-TIM3 or anti-TIGIT Antibodies to anti-PD1 Blockade Augments Human T cell Adoptive Cell Transfer. Oncoimmunology. 2021;10:1873607 pubmed publisher
Reches A, Ophir Y, Stein N, Kol I, Isaacson B, Charpak Amikam Y, et al. Nectin4 is a novel TIGIT ligand which combines checkpoint inhibition and tumor specificity. J Immunother Cancer. 2020;8: pubmed publisher
product information
master code :
MAB7898
SKU :
MAB7898
product name :
Human TIGIT Antibody
unit size :
100 ug (also 25 ug)
description :
The Human TIGIT Antibody from R&D Systems is a mouse monoclonal antibody to TIGIT. This antibody reacts with human. The Human TIGIT Antibody has been validated for the following applications: Neutralization,Flow Cytometry,Blockade of Receptor-ligand Interaction,CyTOF-ready.
target :
TIGIT
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
741182
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human TIGIT, Met1-Pro141, Accession # Q495A1
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human TIGIT in ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse TIGIT or recombinant human DNAM-1/CD226 is observed.
gene symbol :
TIGIT
top caption :
Detection of TIGIT antibody in Human Blood Lymphocytes antibody by Flow Cytometry.
accessionNumbers :
Q495A1
applications :
Neutralization,Flow Cytometry,Blockade of Receptor-ligand Interaction,CyTOF-ready
USD :
509 USD
alt names :
T cell immunoreceptor with Ig and ITIM domains, TIGIT, VSIG9, VSTM3, WUCAM
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.