product summary
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company name :
R&D Systems
product type :
antibody
product name :
MCPIP1 Antibody
catalog :
MAB7875
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
604421
reactivity :
human, mouse
application :
western blot, immunoprecipitation
more info or order :
R&D Systems product webpage
citations: 8
Reference
Behrens G, Edelmann S, Raj T, Kronbeck N, Monecke T, Davydova E, et al. Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses. Nat Immunol. 2021;22:1563-1576 pubmed publisher
Li D, Bechara R, Ramani K, Jawale C, Li Y, Kolls J, et al. RTEC-intrinsic IL-17-driven inflammatory circuit amplifies antibody-induced glomerulonephritis and is constrained by Regnase-1. JCI Insight. 2021;6: pubmed publisher
Rios K, Kashyap A, Maynard S, Washington M, Paul S, Schaefer B. CARD19, the protein formerly known as BinCARD, is a mitochondrial protein that does not regulate Bcl10-dependent NF-κB activation after TCR engagement. Cell Immunol. 2020;356:104179 pubmed publisher
Gehring T, Erdmann T, Rahm M, Graß C, Flatley A, O Neill T, et al. MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells. Cell Rep. 2019;29:873-888.e10 pubmed publisher
Rosenbaum M, Gewies A, Pechloff K, Heuser C, Engleitner T, Gehring T, et al. Bcl10-controlled Malt1 paracaspase activity is key for the immune suppressive function of regulatory T cells. Nat Commun. 2019;10:2352 pubmed publisher
Seno K, Munakata Y, Sano M, Kawahara Miki R, Takahashi H, Ohkuchi A, et al. Aggregation of Human Trophoblast Cells into Three-Dimensional Culture System Enhances Anti-Inflammatory Characteristics through Cytoskeleton Regulation. Int J Mol Sci. 2018;19: pubmed publisher
Baens M, Stirparo R, Lampi Y, Verbeke D, Vandepoel R, Cools J, et al. Malt1 self-cleavage is critical for regulatory T cell homeostasis and anti-tumor immunity in mice. Eur J Immunol. 2018;48:1728-1738 pubmed publisher
Wu C, Yang Y, Chen M, Tsai C, Cheng A, Doong S. Autocleavage of the paracaspase MALT1 at Arg-781 attenuates NF-κB signaling and regulates the growth of activated B-cell like diffuse large B-cell lymphoma cells. PLoS ONE. 2018;13:e0199779 pubmed publisher
image
image 1 :
R&D Systems MAB7875 image 1
Detection of Human and Mouse MCPIP1 antibody by Western Blot.
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
MAB7875
SKU :
MAB7875
product name :
MCPIP1 Antibody
description :
The Human/Mouse MCPIP1 Antibody from R&D Systems is a mouse monoclonal antibody to MCPIP1/ZC3H12A. This antibody reacts with human,mouse. The Human/Mouse MCPIP1 Antibody has been validated for the following applications: Immunoprecipitation,Western Blot.
target :
MCPIP1
unit size :
100 ug (also 25 ug)
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
604421
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human MCPIP1, Asp426-Glu599, Accession # Q5D1E8
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human MCPIP1 in direct ELISAs and human and mouse MCPIP1 in Western blots. In direct ELISAs, no cross-reactivity with recombinant human MCPIP3 is observed.
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
gene symbol :
ZC3H12A
accessionNumbers :
Q5D1E8
applications :
Immunoprecipitation,Western Blot
product keywords :
MAB7875, h/mMCPIP1 MAb (Cl 604421), Mouse Anti-Human/Mouse MCPIP1 Monoclonal Antibody, Mouse Anti Human/Mouse MCPIP1 Monoclonal Antibody, Anti-MCPIP1, Anti-hMCPIP1, Anti-mMCPIP1, MCPIP 1, MCP-1 induced protein 1, CCCH-zinc finger protein, MCP induced protein 1, ribonuclease ZC3H12A, Rnase
USD :
469
USD 2025 :
489 USD
alt names :
Reg1, Regnase-1, ZC3H12A, zinc finger CCCH-type containing 12A
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.