product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-22 Antibody
catalog :
MAB7822-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
489 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
142906
reactivity :
human, mouse
application :
western blot, ELISA
more info or order :
citations: 8
Reference
Min H, Moon J, Lee S, Lee A, Lee C, Lee J, et al. Expanded IL-22+ Group 3 Innate Lymphoid Cells and Role of Oxidized LDL-C in the Pathogenesis of Axial Spondyloarthritis with Dyslipidaemia. Immune Netw. 2021;21:e43 pubmed publisher
Kunkl M, Amormino C, Frascolla S, Sambucci M, De Bardi M, Caristi S, et al. CD28 Autonomous Signaling Orchestrates IL-22 Expression and IL-22-Regulated Epithelial Barrier Functions in Human T Lymphocytes. Front Immunol. 2020;11:590964 pubmed publisher
Zheng W, Li L, Zhao D, Wang O, Jiang Y, Xia W, et al. A novel variant in AIRE causing a rare, non‑classical autoimmune polyendocrine syndrome type 1. Mol Med Rep. 2020;22:1285-1294 pubmed publisher
Zhang J, Friberg I, Kift Morgan A, Parekh G, Morgan M, Liuzzi A, et al. Machine-learning algorithms define pathogen-specific local immune fingerprints in peritoneal dialysis patients with bacterial infections. Kidney Int. 2017;92:179-191 pubmed publisher
Sullivan J, Jankowska Gan E, Hegde S, Pestrak M, Agashe V, Park A, et al. Th17 Responses to Collagen Type V, kα1-Tubulin, and Vimentin Are Present Early in Human Development and Persist Throughout Life. Am J Transplant. 2017;17:944-956 pubmed publisher
Meller S, Di Domizio J, Voo K, Friedrich H, Chamilos G, Ganguly D, et al. T(H)17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26. Nat Immunol. 2015;16:970-9 pubmed publisher
Heo Y, Joo Y, Oh H, Park M, Heo Y, Cho M, et al. IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients. Immunol Lett. 2010;127:150-6 pubmed publisher
Aujla S, Chan Y, Zheng M, Fei M, Askew D, Pociask D, et al. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat Med. 2008;14:275-81 pubmed publisher
product information
master code :
MAB7822
SKU :
MAB7822-100
product name :
Human IL-22 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human IL-22 Antibody from R&D Systems is a mouse monoclonal antibody to IL-22. This antibody reacts with human,mouse. The Human IL-22 Antibody has been validated for the following applications: ELISA Detection,Western Blot,ELISA Development,ELISA Development (Capture),ELISpot Development,ELISA Capture (Matched Antibody Pair).
target :
IL-22
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
142906
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human IL-22, Ala34-Ile179, Accession # Q9GZX6
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human IL-22 in direct ELISAs and Western blots. Shows 100% cross-reactivity with recombinant mouse (rm) IL-22 and recombinant rat IL-22 and no cross-reactivity with recombinant human IL-10. In sandwich ELISAs, no cross-reactivity was observed with rmIL-22, rrIL-22, rhIL-10, rhIL-22BP, or rhIL-22 R.
gene symbol :
IL22
accessionNumbers :
Q9GZX6
applications :
Western Blot,ELISA Development,ELISA Development (Capture),ELISpot Development,ELISA Capture (Matched Antibody Pair)
USD :
489 USD
alt names :
Cytokine Zcyto18, IL-10-related T-cell-derived inducible factor, IL22, IL-D110, IL-TIF, ILTIFIL-10-related T-cell-derived-inducible factor, IL-TIFMGC79382, interleukin 22, interleukin-22, MGC79384, TIFa, TIFIL-23, zcyto18
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.