product summary
Loading...
company name :
R&D Systems
product type :
antibody
product name :
IL-22 Antibody
catalog :
MAB7821-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
442 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
142928
reactivity :
human
application :
neutralization
more info or order :
R&D Systems product webpage
citations: 5
Reference
Chen J, Haller C, Jernigan F, Koerner S, Wong D, Wang Y, et al. Modulation of lymphocyte-mediated tissue repair by rational design of heterocyclic aryl hydrocarbon receptor agonists. Sci Adv. 2020;6:eaay8230 pubmed publisher
Zhang F, Shang D, Zhang Y, Tian Y. Interleukin-22 suppresses the growth of A498 renal cell carcinoma cells via regulation of STAT1 pathway. PLoS ONE. 2011;6:e20382 pubmed publisher
Chang Y, Al Alwan L, Risse P, Roussel L, Rousseau S, Halayko A, et al. TH17 cytokines induce human airway smooth muscle cell migration. J Allergy Clin Immunol. 2011;127:1046-53.e1-2 pubmed publisher
Res P, Piskin G, de Boer O, van der Loos C, Teeling P, Bos J, et al. Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis. PLoS ONE. 2010;5:e14108 pubmed publisher
Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, et al. IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes. J Immunol. 2010;184:4880-8 pubmed publisher
image
image 1 :
R&D Systems MAB7821-100 image 1
IL-10 Secretion Induced by IL-22 and Neutralization by Human IL-22 Antibody.
product information
brand :
R&D Systems
master code :
MAB7821
SKU :
MAB7821-100
product name :
IL-22 Antibody
description :
The Human IL-22 Antibody from R&D Systems is a mouse monoclonal antibody to IL-22. This antibody reacts with human. The Human IL-22 Antibody has been validated for the following applications: Neutralization.
target :
IL-22
category :
Primary Antibodies
unit sizes :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
142928
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human IL-22, Ala34-Ile179, Accession # Q9GZX6
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human IL-22 in direct ELISAs. In direct ELISAs, this antibody shows 100% cross-reactivity with recombinant mouse IL-22 and recombinant rat IL-22 and no cross-reactivity with recombinant human IL-10.
gene symbol :
IL22
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
accessionNumbers :
Q9GZX6
applications :
Neutralization
USD :
442 USD
alt names :
Cytokine Zcyto18, IL-10-related T-cell-derived inducible factor, IL22, IL-D110, IL-TIF, ILTIFIL-10-related T-cell-derived-inducible factor, IL-TIFMGC79382, interleukin 22, interleukin-22, MGC79384, TIFa, TIFIL-23, zcyto18
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.