Human/Mouse/Rat TDP-43/TARDBP Antibody | R&D Systems MAB7778 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat TDP-43/TARDBP Antibody

catalog :

MAB7778

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

671834

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 5d	Devoy A, Price G, De Giorgio F, Bunton Stasyshyn R, Thompson D, Gasco S, et al. Generation and analysis of innovative genomically humanized knockin SOD1, TARDBP (TDP-43), and FUS mouse models. iScience. 2021;24:103463 pubmed publisher
	Worrall D, Ayoubi R, Fotouhi M, Southern K, McPherson P, Laflamme C. The identification of high-performing antibodies for TDP-43 for use in Western Blot, immunoprecipitation and immunofluorescence. F1000Res. 2023;12:277 pubmed publisher
	Feng T, Luan L, Katz I, Ullah M, Van Deerlin V, Trojanowski J, et al. TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss. Acta Neuropathol Commun. 2022;10:33 pubmed publisher
	Uehara K, Koyanagi Aoi M, Koide T, Itoh T, Aoi T. Epithelial-derived factors induce muscularis mucosa of human induced pluripotent stem cell-derived gastric organoids. Stem Cell Reports. 2022;17:820-834 pubmed publisher
	Matsukawa K, Kukharsky M, Park S, Park S, Watanabe N, Iwatsubo T, et al. Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy. RNA Biol. 2021;:1-9 pubmed publisher
	Feng T, Mai S, Roscoe J, Sheng R, Ullah M, Zhang J, et al. Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice. EMBO Rep. 2020;21:e50219 pubmed publisher
	Shelkovnikova T, Kukharsky M, An H, Dimasi P, Alexeeva S, Shabir O, et al. Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis. Mol Neurodegener. 2018;13:30 pubmed publisher

product information

master code :

MAB7778

SKU :

MAB7778

product name :

Human/Mouse/Rat TDP-43/TARDBP Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat TDP-43/TARDBP Antibody from R&D Systems is a mouse monoclonal antibody to TDP-43/TARDBP. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat TDP-43/TARDBP Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunoprecipitation,Simple Western,Immunocytochemistry.

target :

TDP-43/TARDBP

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

671834

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human TDP-43/TARDBP, Met1-Thr103, Accession # Q13148

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects human TDP-43/TARDBP in direct ELISAs. Detects human, mouse, and rat TDP-43/TARDBP in Western blots.

gene symbol :

TARDBP

top caption :

Detection of Human TDP-43/TARDBP antibody by Western Blot.

accessionNumbers :

Q13148

applications :

Western Blot,Immunohistochemistry,Immunoprecipitation,Simple Western,Immunocytochemistry

USD :

489 USD

alt names :

ALS10, ALS10TAR DNA-binding protein-43, TAR DNA binding protein, TARDBP, TDP43, TDP-43, TDP-43TAR DNA-binding protein 43

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage