Human FBXW7/Cdc4 Antibody | R&D Systems MAB7776 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human FBXW7/Cdc4 Antibody

catalog :

MAB7776

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

800201

reactivity :

human, mouse

application :

western blot, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 3

Reference
Xia H, Scholtes C, Dufour C, Ouellet C, Ghahremani M, Giguere V. Insulin action and resistance are dependent on a GSK3β-FBXW7-ERRα transcriptional axis. Nat Commun. 2022;13:2105 pubmed publisher
Wang J, Zhu B, Patterson L, Rogan M, Kibler C, McBride J. Ehrlichia chaffeensis TRP120-mediated ubiquitination and proteasomal degradation of tumor suppressor FBW7 increases oncoprotein stability and promotes infection. PLoS Pathog. 2020;16:e1008541 pubmed publisher
Park J, Kang H, Lee Y, Kang H, Kim J, Chung J, et al. Inactivation of EWS reduces PGC-1Î± protein stability and mitochondrial homeostasis. Proc Natl Acad Sci U S A. 2015;112:6074-9 pubmed publisher

product information

master code :

MAB7776

SKU :

MAB7776

product name :

Human FBXW7/Cdc4 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human FBXW7/Cdc4 Antibody from R&D Systems is a mouse monoclonal antibody to FBXW7/Cdc4. This antibody reacts with human,mouse. The Human FBXW7/Cdc4 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry.

target :

FBXW7/Cdc4

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

800201

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human FBXW7/Cdc4, Lys377-Lys707, Accession # Q969H0

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human FBXW7/Cdc4 in direct ELISAs.

gene symbol :

FBXW7

top caption :

Detection of Human FBXW7/Cdc4 antibody by Western Blot.

accessionNumbers :

Q969H0

applications :

Western Blot,Immunocytochemistry

USD :

469 USD

alt names :

AGO, AGOFBXO30, Archipelago homolog, archipelago, Drosophila, homolog of, Cdc4, CDC4FLJ16457, F-box and WD repeat domain containing 7, F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila), F-box and WD-40 domain-containing protein 7, F-box protein FBW7, F-box protein FBX30, F-box protein SEL-10, F-box/WD repeat-containing protein 7, FBW6, Fbw7, FBW7hCdc4, FBX30, FBX30FLJ11071, FBXO30, FBXW6, hAgo, homolog of C elegans sel-10, SCF(Fbw7), SEL10, SEL-10DKFZp686F23254, SEL10FBW6

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage