Aldo-keto Reductase 1C3/AKR1C3 Antibody | R&D Systems MAB7678 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Aldo-keto Reductase 1C3/AKR1C3 Antibody

catalog :

MAB7678

quantity :

100 ug (also 25 ug)

price :

429 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

871701

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 3

Reference
Zhou C, Wang Z, Li J, Wu X, Fan N, Li D, et al. Aldo-Keto Reductase 1C3 Mediates Chemotherapy Resistance in Esophageal Adenocarcinoma via ROS Detoxification. Cancers (Basel). 2021;13: pubmed publisher
Verma K, Zang T, Penning T, Trippier P. Potent and Highly Selective Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors Act as Chemotherapeutic Potentiators in Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia. J Med Chem. 2019;62:3590-3616 pubmed publisher
Savchuk I, Morvan M, Antignac J, Gemzell Danielsson K, le Bizec B, Soder O, et al. Androgenic potential of human fetal adrenals at the end of the first trimester. Endocr Connect. 2017;6:348-359 pubmed publisher

image

image 1 :

Detection of Human Aldo-keto Reductase 1C3/AKR1C3 antibody by Western Blot.

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB7678

SKU :

MAB7678

product name :

Aldo-keto Reductase 1C3/AKR1C3 Antibody

Description :

The Human Aldo-keto Reductase 1C3/AKR1C3 Antibody from R&D Systems is a mouse monoclonal antibody to Aldo-keto Reductase 1C3/AKR1C3. This antibody reacts with human. The Human Aldo-keto Reductase 1C3/AKR1C3 Antibody has been validated for the following applications: Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry.

target :

Aldo-keto Reductase 1C3/AKR1C3

category :

Primary Antibodies

unit size :

100 ug (also 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

871701

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human Aldo-keto Reductase 1C3/AKR1C3, Asp2-Tyr323, Accession # P42330

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Aldo-keto Reductase 1C3/AKR1C3 in ELISAs and Western Blot.

gene symbol :

AKR1C3

accessionNumbers :

P42330

applications :

Western Blot, Simple Western, Immunohistochemistry, Immunocytochemistry

USD :

429 USD

alt names :

17-beta-hydroxysteroid dehydrogenase type 5, 3-alpha-HSD type 2, 3-alpha-hydroxysteroid dehydrogenase type 2, AKR1C3, aldo-keto reductase family 1 member C3, aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II), AldoketoReductase 1C3, Chlordecone reductase homolog HAKRb, DD3, DD-3, DD317-beta-HSD 5, DDH1, DDX, Dihydrodiol dehydrogenase 3, Dihydrodiol dehydrogenase type I, dihydrodiol dehydrogenase X, EC 1.1.1, EC 1.1.1.112,3-alpha-HSD type II, brain, EC 1.1.1.188, EC 1.1.1.213, EC 1.1.1.63, EC 1.1.1.64, EC 1.3.1.20, HA1753, HAKRB, HAKRBtype IIb 3-alpha hydroxysteroid dehydrogenase, HAKRe, HSD17B5, hydroxysteroid (17-beta) dehydrogenase 5, Indanol dehydrogenase, KIAA0119hluPGFS, PGFS, Prostaglandin F synthase, Testosterone 17-beta-dehydrogenase 5, Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage