Human FGFR3 (IIIc) Antibody | R&D Systems MAB7662-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human FGFR3 (IIIc) Antibody

catalog :

MAB7662-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

136312

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 3

Reference
Gonçalvès D, Rignol G, Dellugat P, Hartmann G, Sarrazy Garcia S, Stavenhagen J, et al. In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia. PLoS ONE. 2020;15:e0244368 pubmed publisher
Ueno N, Shimizu A, Kanai M, Iwaya Y, Ueda S, Nakayama J, et al. Enhanced Expression of Fibroblast Growth Factor Receptor 3 IIIc Promotes Human Esophageal Carcinoma Cell Proliferation. J Histochem Cytochem. 2016;64:7-17 pubmed publisher
Tomlinson D, L Hôte C, Kennedy W, Pitt E, Knowles M. Alternative splicing of fibroblast growth factor receptor 3 produces a secreted isoform that inhibits fibroblast growth factor-induced proliferation and is repressed in urothelial carcinoma cell lines. Cancer Res. 2005;65:10441-9 pubmed

product information

master code :

MAB7662

SKU :

MAB7662-100

product name :

Human FGFR3 (IIIc) Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human FGFR3 (IIIc) Antibody from R&D Systems is a mouse monoclonal antibody to FGFR3. This antibody reacts with human,mouse,n/a. The Human FGFR3 (IIIc) Antibody has been validated for the following applications: Bioassay,Immunohistochemistry,Western Blot,Immunocytochemistry,Immunoprecipitation,ELISA Capture,Flow Cytometry.

target :

FGFR3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

136312

conjugate :

Unconjugated

host :

Mouse

immunogen :

Pool of NS0-derived recombinant human FGF R3 alpha (IIIb) and Sf21-derived FGF R3 alpha (IIIc)

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,N/A

specificity :

Detects human FGF R3 (IIIc) in direct ELISAs and Western blots. In direct ELISAs, 100% cross-reactivity with recombinant human (rh) FGF R2 (IIIc), recombinant mouse (rm) FGF R2 (IIIc) and rmFGF R3 (IIIc) is observed. In Western blots (non-reducing conditions only), 50-100% cross-reactivity with rhFGF R2 (IIIc), rmFGF R2 (IIIc) and rmFGF R3 (IIIc) is observed.

gene symbol :

FGFR3

applications :

Bioassay,Immunohistochemistry,Western Blot,Immunocytochemistry,Immunoprecipitation,ELISA Capture,Flow Cytometry

extended description :

Clone 136312 was used by HLDA to establish CD designation

USD :

489 USD

product details :

Clone 136312 was used by HLDA to establish CD designation

alt names :

CD333, CEK, EC 2.7.10, FGF R3, fibroblast growth factor receptor 3, HSFGFR3EX, JTK4, JTK4thanatophoric dwarfism

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage